| Identification | Back Directory | [Name]
Spiro[8H-naphth[2',1':4,5]indeno[2,1-b]furan-8,2'-[2H]pyran] alpha-D-glucopyranoside deriv. | [CAS]
76296-71-4 | [Synonyms]
Polyphillin C
Prosapogenin A of gracillin
Spiro[8H-naphth[2',1':4,5]indeno[2,1-b]furan-8,2'-[2H]pyran] alpha-D-glucopyranoside deriv. | [Molecular Formula]
C39H62O12 | [MOL File]
76296-71-4.mol | [Molecular Weight]
722.902 |
| Chemical Properties | Back Directory | [Melting point ]
189-192℃ | [Boiling point ]
849.1±65.0 °C(Predicted) | [density ]
1.34 | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Powder | [pka]
12.70±0.70(Predicted) |
| Hazard Information | Back Directory | [Uses]
Polyphyllin C (compound 2) is a spirostanol saponin. Polyphyllin C exhibits mild (IC50=36.87?μM) activities against the tyrosinase and moderate (IC50=1.59 μg/mL) antileishmanial activities[1][2]. | [References]
[1] Devkota KP, et, al. Tyrosinase inhibitory and antileishmanial constituents from the rhizomes of Paris polyphylla. Nat Prod Res. 2007 Apr;21(4):321-7. DOI:10.1080/14786410701192777
[2] Singh SB, et, al. Spirostanol saponins from Paris polyphylla, structures of polyphyllin C, D, E and F. Phytochemistry.1980; 21(12): 2925-2929. |
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