| Identification | More | [Name]
1-Butylpyrrolidine | [CAS]
767-10-2 | [Synonyms]
1-BUTYLPYRROLIDINE
N-BUTYL PYRROLIDINE
1-butyl-pyrrolidin
N-butyl-Tetrahydropyrrole
Pyrrolidine, 1-butyl- | [EINECS(EC#)]
212-179-4 | [Molecular Formula]
C8H17N | [MDL Number]
MFCD00003184 | [Molecular Weight]
127.23 | [MOL File]
767-10-2.mol |
| Safety Data | Back Directory | [Hazard Codes ]
T | [Risk Statements ]
R10:Flammable.
R24/25:Toxic in contact with skin and if swallowed . | [Safety Statements ]
S16:Keep away from sources of ignition-No smoking .
S36/37:Wear suitable protective clothing and gloves .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [RIDADR ]
UN 2929 6.1/PG 2
| [WGK Germany ]
2
| [RTECS ]
UX9800000
| [HazardClass ]
3.2 | [PackingGroup ]
III |
| Hazard Information | Back Directory | [Uses]
1-Butylpyrrolidine can be used in the composition for alcohol recovery solution. | [Preparation]
The synthesis of 1-butylpyrrolidine and its derivatives (1-butylpyrrolidine with a little of 1-butenylpyrrolidines) was developed via a one-pot method from ammonia and 1,4-butandiol. Here, the product of 1-butylpyrrolidine was emphatically investigated, and the yield was 76% under the optimized conditions. Such a route was realized through successive N-alkylation using aqueous ammonia as the nitrogen source over the CuNiPd/ZSM-5 catalyst, which was prepared by a simple incipient wetness method. In this route, 1,4-butandiol not only participated in the formation of the N-heterocycle, but also acted as an alkylating reagent. This work offers a straightforward, economical route for 1-butylpyrrolidine and its derivatives.
One-pot synthesis of 1-butylpyrrolidine and its derivatives from aqueous ammonia and 1,4-butandiol over CuNiPd/ZSM-5 catalysts |
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