| Identification | More | [Name]
Choline dihydrogencitrate salt | [CAS]
77-91-8 | [Synonyms]
(2-HYDROXYETHYL)TRIMETHYLAMMONIUM CITRATE
[2-HYDROXYETHYL]TRIMETHYLAMMONIUM DIHYDROGEN CITRATE SALT
CHOLINE CITRATE
CHOLINE DIHYDROGEN CITRATE
CHOLINE DIHYDROGEN CITRATE SALT
CHOTHYN
CIRROCOLINA
CITRACHOLINE
SALTS OF (2-HYDROXYETHYL)TRIMETHYLAMMONIUM
Choline Dihydrogen Citrate Coated
Choline Dihydrogen Citrate Uncoated
CholineDihydrogenCitrateN.F.Xii
Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, salt with 2-hydroxy-1,2,3-propanetricarboxylic acid (1:1)
CHOLINEDIHYDR
(2-Hydroxyethyl)trimethylammonium dihydrogen citrate
Cholinvel
Citracol
Colicitrin
Coline citrate
Coline dihydrogen citrate | [EINECS(EC#)]
201-068-6 | [Molecular Formula]
C21H47N3O10 | [MDL Number]
MFCD00038734 | [Molecular Weight]
501.61 | [MOL File]
77-91-8.mol |
| Chemical Properties | Back Directory | [Appearance]
White crystalline powder | [Melting point ]
105-107.5° | [storage temp. ]
2-8°C
| [solubility ]
DMSO (Slightly, Heated), Methanol (Slightly), Water (Slightly) | [form ]
Solid | [color ]
White to Off-White | [Water Solubility ]
almost transparency | [Merck ]
2207 | [Stability:]
Hygroscopic | [InChI]
InChI=1S/C6H8O7.C5H14NO/c7-3(8)1-6(13,5(11)12)2-4(9)10;1-6(2,3)4-5-7/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);7H,4-5H2,1-3H3/q;+1/p-1 | [InChIKey]
WRPUOFKIGGWQIJ-UHFFFAOYSA-M | [SMILES]
C(O)(C(=O)O)(CC([O-])=O)CC(=O)O.C(CO)[N+](C)(C)C | [LogP]
-1.721 (est) | [CAS DataBase Reference]
77-91-8(CAS DataBase Reference) | [EPA Substance Registry System]
77-91-8(EPA Substance) |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS07 | [Signal word ]
Warning | [Hazard statements ]
H315-H319-H335 | [Precautionary statements ]
P261-P264-P271-P280-P302+P352-P305+P351+P338 | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [WGK Germany ]
2
| [RTECS ]
GA2582000
| [TSCA ]
TSCA listed | [REACH Registrations]
Active | [HS Code ]
29231000 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| Hazard Information | Back Directory | [Chemical Properties]
White crystalline powder | [Originator]
Chothyn, Flint, US,1945 | [Uses]
Choline Dihydrogen Citrate can be used to synthesize compounds that can improve the photosynthetic efficiency of plants. It can also be used for synthesizing cleaning compounds that can be used for dishwashing, oven cleaning, microwave oven cleaning, floor cleaning, or surface cleaning. Furthermore, Choline Dihydrogen Citrate can potentially be used in the treatment of multiple sclerosis. Additionally, Choline Dihydrogen Citrate can also be use as a component of a nutritional supplement that can be used for improving cerebral activity. | [Manufacturing Process]
30 lb of trimethylamine were added to 70.4 lb of methyl alcohol to which 9.2
lb of water had previously been added. To the resulting solution in a closed
vessel 23 lb of ethylene oxide gas were introduced and the resulting mixture
then maintained at a temperature of 16 C to 30 C and agitated for 6 hours.
During the reaction the pressure in the reaction vessel varied from about 17.5
psi at the start of the reaction to 0 psi at the end of the reaction. The
resulting solution was then added with agitation to a refluxing solution of 40
liters of isopropyl alcohol containing 95 lb of citric acid dissolved therein. This
mixture was then cooled to 0°C and held at that temperature overnight. The
white crystalline choline dihydrogen citrate which formed was separated from
the solvent mixture by filtration and dried in vacuo. 117 lb of anhydrous,
crystalline choline dihydrogen citrate having a purity of 99.6% were obtained.
This was a yield of 78% based on the amount of trimethylamine employed. | [Therapeutic Function]
Lipotropic | [Biochem/physiol Actions]
Acyl group acceptor |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Energy Chemical
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400-0056266 |
| Website: |
www.energy-chemical.com |
| Company Name: |
Spectrum Chemical Manufacturing Corp.
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| Telephone: |
021-021-021-67601398-809-809-809 15221380277 |
| Website: |
www.spectrumchemical.com/oa_html/index.jsp?minisite=10020&respid=22372&language=us |
| Company Name: |
Sigma-Aldrich
|
| Telephone: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
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