| Identification | More | [Name]
4-(CHLOROMETHYL)THIAZOLE HYDROCHLORIDE | [CAS]
7709-58-2 | [Synonyms]
4-(CHLOROMETHYL)-1,3-THIAZOLE
4-(CHLOROMETHYL)-1,3-THIAZOLE HYDROCHLORIDE
4-CHLOROMETHYL-THIAZOLE
4-(CHLOROMETHYL)THIAZOLE HCL
4-(CHLOROMETHYL)THIAZOLE HYDROCHLORIDE
CHLOROMETHYLTHIAZOLE-4 HCL
chloromethylthiazolehydrochloride | [EINECS(EC#)]
672-064-3 | [Molecular Formula]
C4H5Cl2NS | [MDL Number]
MFCD02094738 | [Molecular Weight]
170.06 | [MOL File]
7709-58-2.mol |
| Chemical Properties | Back Directory | [Melting point ]
166-167 °C (sublm) | [storage temp. ]
Inert atmosphere,Room Temperature | [form ]
powder to crystal | [color ]
White to Light yellow | [InChI]
InChI=1S/C4H4ClNS.ClH/c5-1-4-2-7-3-6-4;/h2-3H,1H2;1H | [InChIKey]
NVTBASMQHFMANH-UHFFFAOYSA-N | [SMILES]
S1C=C(CCl)N=C1.[H]Cl | [CAS DataBase Reference]
7709-58-2(CAS DataBase Reference) |
| Safety Data | Back Directory | [Symbol(GHS) ]
 
GHS05,GHS07 | [Signal word ]
Danger | [Hazard statements ]
H302-H318 | [Precautionary statements ]
P280-P305+P351+P338 | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . | [WGK Germany ]
3 | [HazardClass ]
IRRITANT | [HS Code ]
2934100090 |
| Hazard Information | Back Directory | [Chemical Properties]
White crystalline | [Uses]
4-(Chloromethyl)thiazole hydrochloride and its derivatives can be used to prepare 4-thiazole carboxylic acid. It has been shown that in the study of synthesis of conformationally restricted RGD-containing integrin ligands by efficient solid-phase intramolecular thioalkylation, the reaction of S-nucleophiles with the newly generated N-terminal 4-chloromethyl thiazoles afforded the desired cyclic RGD product 5 with high purity and good overall yield[1]. | [References]
[1] ADEL NEFZI Jason E F. N-terminus 4-chloromethyl thiazole peptide as a macrocyclization tool in the synthesis of cyclic peptides: application to the synthesis of conformationally constrained RGD-containing integrin ligands[J]. Tetrahedron Letters, 2011. DOI:10.1016/j.tetlet.2010.12.043. |
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| Company Name: |
J & K SCIENTIFIC LTD.
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| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
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