| Identification | More | [Name]
Nefiracetam | [CAS]
77191-36-7 | [Synonyms]
n-(2,6-dimethylphenyl)-2-oxo-1-pyrrolidineacetamide
NEFIRACETAM
2-oxo-1-pyrrolidinylaceticacid,2,6-dimethylanilide
dm9384
dmppa
n-(2,6-dimethylphenyl)-2-oxo-1-pyrrolidineacetamid
DM-9384, (2-(2-Oxopyrrolidin-1-yl)-N-(2,6-dimethylphenyl)-acetamide)
DMMPA
DZL-221
Translon
2',6'-Dimethyl-2-(2-oxo-1-pyrrolidinyl)acetoanilide
N-(2,6-Dimethylphenyl)-2-(2-oxopyrrolidin-1-yl)acetamide | [EINECS(EC#)]
636-080-4 | [Molecular Formula]
C14H18N2O2 | [MDL Number]
MFCD00209882 | [Molecular Weight]
246.3 | [MOL File]
77191-36-7.mol |
| Chemical Properties | Back Directory | [Melting point ]
151-155°C | [Boiling point ]
458.5±33.0 °C(Predicted) | [density ]
1.187±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
DMSO: >5mg/mL | [form ]
solid | [pka]
13.77±0.70(Predicted) | [color ]
white to off-white | [Merck ]
14,6439 | [InChI]
InChI=1S/C14H18N2O2/c1-10-5-3-6-11(2)14(10)15-12(17)9-16-8-4-7-13(16)18/h3,5-6H,4,7-9H2,1-2H3,(H,15,17) | [InChIKey]
NGHTXZCKLWZPGK-UHFFFAOYSA-N | [SMILES]
N1(CC(NC2=C(C)C=CC=C2C)=O)CCCC1=O | [CAS DataBase Reference]
77191-36-7(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R22:Harmful if swallowed. | [WGK Germany ]
3 | [RTECS ]
UX9655650 | [HS Code ]
2933.79.1500 | [Toxicity]
LD50 in mice (mg/kg): 421 i.v.; 1766 orally (Betzing, 1982) |
| Hazard Information | Back Directory | [Uses]
analgesic, antiinflammatory | [Definition]
ChEBI: Nefiracetam is an organooxygen compound and an organonitrogen compound. It is functionally related to an alpha-amino acid. | [Biological Activity]
Cognitive enhancer that displays various pharmacological effects. Activates L/N-type calcium channels, cholinergic, monoaminergic and GABAergic systems. Displays potent neuroprotective action in the retinal ischemia-reperfusion model in vivo . | [storage]
Store at -20°C |
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