| Identification | Back Directory | [Name]
4-AMINOBENZAMIDINE HYDROCHLORIDE | [CAS]
7761-72-0 | [Synonyms]
TIMTEC-BB SBB003838
P-AMINOBENZAMIDINE HCL
4-AMINOBENZIMIDAMIDE HCL
p-aminobenzamidinehydrochloride
4-AMINOBENZAMIDINE HYDROCHLORIDE
4-Aminobenzimidamide hydrochloride
p-amino-benzamidinmonohydrochloride
4-Aminobenzamidine monohydrochloride
4-aminobenzenecarboximidamide hydrochloride
4-azanylbenzenecarboximidamide hydrochloride
4-aMinobenzene-1-carboxiMidaMide hydrochloride
4-aminobenzenecarboximidamidemonohydrochloride
4-amino-benzenecarboximidamidmonohydrochloride | [Molecular Formula]
C7H10ClN3 | [MDL Number]
MFCD00077095 | [MOL File]
7761-72-0.mol | [Molecular Weight]
171.63 |
| Hazard Information | Back Directory | [Uses]
4-Aminobenzimidamide Hydrochloride (Compound 4a) is a MRGPRX1 agonist. 4-Aminobenzimidamide Hydrochloride can be used in the study of MRGPRX1-mediated analgesic effects[1]. | [Synthesis]
4-aminophenyl ethyl imino ether hydrochloride(3.0 g) was added to a solution of ammonia (12g) in ethanol(150ml, ~8% mass percent) with stirring at room temperature for 24 hours. The reaction mixture was filtered and concentrated in vacuo, and acidated with hydrochloric acid (5ml, 63%). Absorbent charcoal was used to purify. The mixture was filtered, and concentrated and dried in vacuo at room temperature to give 5.0 g(86%) of 4-aminobenzamidine hydrochloride was obtained as a bright yellow solid. | [References]
[1] Prchalová E, et al. Discovery of Benzamidine- and 1-Aminoisoquinoline-Based Human MAS-Related G-Protein-Coupled Receptor X1 (MRGPRX1) Agonists. J Med Chem. 2019 Sep 26;62(18):8631-8641. DOI:10.1021/acs.jmedchem.9b01003 |
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| Company Name: |
J & K SCIENTIFIC LTD.
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18210857532 18210857532 |
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https://www.jkchemical.com |
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