ChemicalBook--->CAS DataBase List--->78287-27-1

78287-27-1

78287-27-1 Structure

78287-27-1 Structure
IdentificationMore
[Name]

7-Ethylcamptothecin
[CAS]

78287-27-1
[Synonyms]

7-ETHYL-CAMPTOTHECIN,HPLC 99%
(S)-4,11-Diethyl-4-hydroxy-1H-pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione
(4S)-4,11-Diethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
SN 22
7-Etyl-camptothecin
(4S)-4,11-Diethyl-4-hydroxy-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-dione
[Molecular Formula]

C22H20N2O4
[MDL Number]

29349990
[Molecular Weight]

376.4
[MOL File]

78287-27-1.mol
Chemical PropertiesBack Directory
[Appearance]

Light Pink Solid
[Melting point ]

236-241°C
[Boiling point ]

752.9±60.0 °C(Predicted)
[density ]

1.43
[storage temp. ]

Sealed in dry,2-8°C
[solubility ]

Chloroform and Methanol Mixture (Slightly, Heated, Sonicated), DMSO (Slightly, Heated)
[form ]

Solid
[pka]

11.24±0.20(Predicted)
[color ]

Pale Yellow to Light Orange
[Usage]

An anticancer drug, showed strong activity against various murine tumors. A Camptothecin (CPT) derivative as antineoplastic agent against drug-resistant tumors.
[InChIKey]

MYQKIWCVEPUPIL-JOCHJYFZSA-N
[CAS DataBase Reference]

78287-27-1(CAS DataBase Reference)
Safety DataBack Directory
[Risk Statements ]

23/34/35
[Safety Statements ]

3/14-6-36/37/39
[RIDADR ]

1544
[HazardClass ]

6.1
[PackingGroup ]

III
[HS Code ]

29349990
Hazard InformationBack Directory
[Chemical Properties]

Light Pink Solid
[Uses]

An anticancer drug, showed strong activity against various murine tumors. A Camptothecin (CPT) derivative as antineoplastic agent against drug-resistant tumors.
[Uses]

An anticancer drug, showed strong activity against various murine tumors. A Camptothecin (CPT) derivative as antineoplastic agent against drug-resistant tumors. Irinotecan USP Related Compound E.
[Definition]

ChEBI: 7-ethylcamptothecin is a pyranoindolizinoquinoline.
[Biological Activity]

7-Ethylcamptothecin is one of the camptothecin analogs. Camptothecin (CPT), a cytotoxic alkaloid isolated from camptothecin analogues, has strong antitumor activity against L1210 leukemia and Walker 256 carcinosarcoma models.
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