ChemicalBook--->CAS DataBase List--->788824-64-6

788824-64-6

788824-64-6 Structure

788824-64-6 Structure
IdentificationBack Directory
[Name]

4-[4-(2-Aminoethyl)-2-iodophenoxy]phenol Hydrochloride
[CAS]

788824-64-6
[Synonyms]

3-Iodothyronamine Hydrochloride
4-[4-(2-aminoethyl)-2-iodophenoxy]phenol
4-[4-(2-Aminoethyl)-2-iodophenoxy]phenol Hydrochloride
[Molecular Formula]

C14H15ClINO2
[MDL Number]

MFCD11973725
[MOL File]

788824-64-6.mol
Chemical PropertiesBack Directory
[Melting point ]

209-211°C
[storage temp. ]

Hygroscopic, Refrigerator, Under Inert Atmosphere
[solubility ]

DMF: 50 mg/ml; DMSO: 30 mg/ml; Ethanol: 25 mg/ml; PBS (pH 7.2): 0.1 mg/ml
[form ]

A crystalline solid
[color ]

white to beige
[Water Solubility ]

H2O: 10mg/mL, clear
[InChI]

1S/C14H14INO2.ClH/c15-13-9-10(7-8-16)1-6-14(13)18-12-4-2-11(17)3-5-12;/h1-6,9,17H,7-8,16H2;1H
[InChIKey]

RVKVVMXTPQCCIX-UHFFFAOYSA-N
[SMILES]

OC1=CC=C(OC2=C(I)C=C(CCN)C=C2)C=C1.[H]Cl
Safety DataBack Directory
[Symbol(GHS) ]

GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
GHS07,GHS08,GHS09
[Signal word ]

Danger
[Hazard statements ]

H302-H315-H319-H335-H410-H372
[Precautionary statements ]

P301+P312+P330-P305+P351+P338
[WGK Germany ]

WGK 3
[Storage Class]

11 - Combustible Solids
[Hazard Classifications]

Acute Tox. 4 Oral
Aquatic Acute 1
Aquatic Chronic 1
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
Hazard InformationBack Directory
[Chemical Properties]

White Solid
[Uses]

3-Iodothyronamine is a novel metabolite of thyroid hormone (TH). 3-Iodothyronamine (T1AM) take in rodents.
[Uses]

A novel metabolite of thyroid hormone (TH). 3-Iodothyronamine (T1AM) is an endogenous and rapid-acting derivative of thyroid hormone.
[Biological Activity]

3-iodothyronamine (T1AM) is present in vertebrate tissues and the circulatory system. Its physiological effects are the opposite of the thyroid hormone. T1AM acts as a neuromodulator as well as a hormone-like molecule.''T1AM (3-Iodothyronamine) is an endogenous biogenic amine derived from thyroid hormone. T1AM is a potent agonist of trace amine-associated receptor TAAR1 (TAR1TA1)a GPCR primarily found in the brain.
[storage]

Store at -20°C
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