| Identification | Back Directory | [Name]
Meta Fluoxetine Hydrochloride | [CAS]
79088-29-2 | [Synonyms]
Fluoxetine EP Impurity
Fluoxetine EP IMpurity C
FluoxetineEPImpurityCHCl
Fluoxetine Impurity C HCl
Fluoxetine impurity C CRS
Fluoxetine Impurity 3(EP-C)
Meta Fluoxetine Hydrochloride
Fluoxetine Related CoMpound A
Fluoxetine impurity C (F0253030)
Fluoxetine Impurity C Hydrochloride
Fluoxetine Related Compound A as Hydrochloride
Fluoxetine USP Related Compound A as Hydrochloride
Fluoxetine Hydrochloride Impurity C as Hydrochloride
Fluoxetine Hydrochloride EP Impurity C as Hydrochloride
N-Methyl-γ-[3-(trifluoroMethyl)phenoxy]benzenepropanaMine
N-Methyl-3-phenyl-3-[(α,α,α-trifluoro-m-tolyl)oxy]propylamine
N-Methyl-3-phenyl-3-[(α,α,α-trifluoro-m-tolyl)oxy]propylamine
Fluoxetine EP Impurity C HCl (Fluoxetine USP Related Compound A HCl)
N-Methyl-gamma-[3-(trifluoromethyl)phenoxy]benzenepropanamine hydrochloride
(±)-N-Methyl-(γ-[3-(trifluoromethyl)phenoxy]benzenepropanamine hydrochloride
N-methyl-3-phenyl-3-[3-(trifluoromethyl)phenoxy]propan-1-amine:hydrochloride
(RS)-N-Methyl-3-(3-trifluoromethylphenoxy)-3-phenylpropylamine hydrochloride
(+/-)N-Methyl-y-[3-(trifluoromethyl)-phenoxy]benzenepropanamine hydrochloride
N-Methyl-3-phenyl-3-[(alpha,alpha,alpha-(trifluoro-M-tolyl)oxy]propylaMine Hydrochloride
N-Methyl-3-phenyl-3-(3-(trifluoroMethyl)phenoxy)propan-1-aMine hydrochloride
(RelCpd A)
Fluoxetine Hydrochloride Impurity Ⅳ：N-Methyl-γ-[3-(trifluoromethyl)phenoxy]benzenepropanamine
Fluoxetine Hydrochloride Impurity Ⅳ：N-Methyl-γ-[3-(trifluoromethyl)phenoxy]benzenepropanamine
Fluoxetine Related Compound A (N-methyl-3-phenyl-3-[(alpha, alpha, alpha-trifluoro-m-tolyl)oxy]prop (1279815)
Fluoxetine Related Compound A (15 mg) (N-methyl-3-phenyl-3-[(alpha, alpha, alpha-trifluoro-m-tolyl)oxy]propylamine hydrochloride) | [Molecular Formula]
C17H19ClF3NO | [MDL Number]
MFCD18382385 | [MOL File]
79088-29-2.mol | [Molecular Weight]
345.787 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 16 mg/ml; DMSO: 12.5 mg/ml; Ethanol: 12.5 mg/ml; PBS (pH 7.2): 0.2 mg/ml | [form ]
neat | [Major Application]
pharmaceutical | [InChI]
1S/C17H18F3NO.ClH/c1-21-11-10-16(13-6-3-2-4-7-13)22-15-9-5-8-14(12-15)17(18,19)20;/h2-9,12,16,21H,10-11H2,1H3;1H | [InChIKey]
JCRCCLNIWABPIS-UHFFFAOYSA-N | [SMILES]
CNCCC(C1=CC=CC=C1)OC2=CC(C(F)(F)F)=CC=C2.Cl |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS07 | [Signal word ]
Warning | [Hazard statements ]
H302 | [Precautionary statements ]
P301+P312+P330 | [Hazard Codes ]
Xn | [Risk Statements ]
22 | [RIDADR ]
UN 3077 9 / PGIII | [WGK Germany ]
WGK 3 | [HS Code ]
2922199695 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral |
| Hazard Information | Back Directory | [Description]
meta-Fluoxetine is an isomer of fluoxetine that is found as an impurity in fluoxetine preparations. meta-Fluoxetine is a weaker serotonin selective reuptake inhibitor (SSRI) than fluoxetine, in which the trifluoromethyl group is at the para position (Kis = 166 and 17 nM, respectively, in rat brain synaptosomes). | [Chemical Properties]
Off-White Solid | [Uses]
Fluoxetine (F597100) meta isomer. Fluoxetine impurity. | [References]
[1] D T WONG. A new selective inhibitor for uptake of serotonin into synaptosomes of rat brain: 3-(p-trifluoromethylphenoxy). N-methyl-3-phenylpropylamine.[J]. Journal of Pharmacology and Experimental Therapeutics, 1975, 193 3: 804-811.
[2] DAVID T. WONG Eric A E Frank P Bymaster. Prozac (fluoxetine, lilly 110140), the first selective serotonin uptake inhibitor and an antidepressant drug: Twenty years since its first publication[J]. Life sciences, 1995, 57 5: Pages 411-441. DOI: 10.1016/0024-3205(95)00209-o |
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| Company Name: |
BOC Sciences
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16314854226 |
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www.bocsci.com |
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