ChemicalBook--->CAS DataBase List--->79088-29-2

79088-29-2

79088-29-2 Structure

79088-29-2 Structure
IdentificationBack Directory
[Name]

Meta Fluoxetine Hydrochloride
[CAS]

79088-29-2
[Synonyms]

Fluoxetine EP Impurity
Fluoxetine EP IMpurity C
FluoxetineEPImpurityCHCl
Fluoxetine Impurity C HCl
Fluoxetine impurity C CRS
Fluoxetine Impurity 3(EP-C)
Meta Fluoxetine Hydrochloride
Fluoxetine Related CoMpound A
Fluoxetine impurity C (F0253030)
Fluoxetine Impurity C Hydrochloride
Fluoxetine Related Compound A as Hydrochloride
Fluoxetine USP Related Compound A as Hydrochloride
Fluoxetine Hydrochloride Impurity C as Hydrochloride
Fluoxetine Hydrochloride EP Impurity C as Hydrochloride
N-Methyl-γ-[3-(trifluoroMethyl)phenoxy]benzenepropanaMine
N-Methyl-3-phenyl-3-[(α,α,α-trifluoro-m-tolyl)oxy]propylamine
N-Methyl-3-phenyl-3-[(α,α,α-trifluoro-m-tolyl)oxy]propylamine
Fluoxetine EP Impurity C HCl (Fluoxetine USP Related Compound A HCl)
N-Methyl-gamma-[3-(trifluoromethyl)phenoxy]benzenepropanamine hydrochloride
(±)-N-Methyl-(γ-[3-(trifluoromethyl)phenoxy]benzenepropanamine hydrochloride
N-methyl-3-phenyl-3-[3-(trifluoromethyl)phenoxy]propan-1-amine:hydrochloride
(RS)-N-Methyl-3-(3-trifluoromethylphenoxy)-3-phenylpropylamine hydrochloride
(+/-)N-Methyl-y-[3-(trifluoromethyl)-phenoxy]benzenepropanamine hydrochloride
N-Methyl-3-phenyl-3-[(alpha,alpha,alpha-(trifluoro-M-tolyl)oxy]propylaMine Hydrochloride
N-Methyl-3-phenyl-3-(3-(trifluoroMethyl)phenoxy)propan-1-aMine hydrochloride (RelCpd A)
Fluoxetine Hydrochloride Impurity Ⅳ:N-Methyl-γ-[3-(trifluoromethyl)phenoxy]benzenepropanamine
Fluoxetine Hydrochloride Impurity Ⅳ:N-Methyl-γ-[3-(trifluoromethyl)phenoxy]benzenepropanamine
Fluoxetine Related Compound A (N-methyl-3-phenyl-3-[(alpha, alpha, alpha-trifluoro-m-tolyl)oxy]prop (1279815)
Fluoxetine Related Compound A (15 mg) (N-methyl-3-phenyl-3-[(alpha, alpha, alpha-trifluoro-m-tolyl)oxy]propylamine hydrochloride)
[Molecular Formula]

C17H19ClF3NO
[MDL Number]

MFCD18382385
[MOL File]

79088-29-2.mol
[Molecular Weight]

345.787
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMF: 16 mg/ml; DMSO: 12.5 mg/ml; Ethanol: 12.5 mg/ml; PBS (pH 7.2): 0.2 mg/ml
[form ]

neat
[Major Application]

pharmaceutical
[InChI]

1S/C17H18F3NO.ClH/c1-21-11-10-16(13-6-3-2-4-7-13)22-15-9-5-8-14(12-15)17(18,19)20;/h2-9,12,16,21H,10-11H2,1H3;1H
[InChIKey]

JCRCCLNIWABPIS-UHFFFAOYSA-N
[SMILES]

CNCCC(C1=CC=CC=C1)OC2=CC(C(F)(F)F)=CC=C2.Cl
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302
[Precautionary statements ]

P301+P312+P330
[Hazard Codes ]

Xn
[Risk Statements ]

22
[RIDADR ]

UN 3077 9 / PGIII
[WGK Germany ]

WGK 3
[HS Code ]

2922199695
[Storage Class]

11 - Combustible Solids
[Hazard Classifications]

Acute Tox. 4 Oral
Hazard InformationBack Directory
[Description]

meta-Fluoxetine is an isomer of fluoxetine that is found as an impurity in fluoxetine preparations. meta-Fluoxetine is a weaker serotonin selective reuptake inhibitor (SSRI) than fluoxetine, in which the trifluoromethyl group is at the para position (Kis = 166 and 17 nM, respectively, in rat brain synaptosomes).
[Chemical Properties]

Off-White Solid
[Uses]

Fluoxetine (F597100) meta isomer. Fluoxetine impurity.
[References]

[1] D T WONG. A new selective inhibitor for uptake of serotonin into synaptosomes of rat brain: 3-(p-trifluoromethylphenoxy). N-methyl-3-phenylpropylamine.[J]. Journal of Pharmacology and Experimental Therapeutics, 1975, 193 3: 804-811.
[2] DAVID T. WONG  Eric A E  Frank P Bymaster. Prozac (fluoxetine, lilly 110140), the first selective serotonin uptake inhibitor and an antidepressant drug: Twenty years since its first publication[J]. Life sciences, 1995, 57 5: Pages 411-441. DOI: 10.1016/0024-3205(95)00209-o
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