| Identification | Back Directory | [Name]
Renin Substrate 1 trifluoroacetate salt | [CAS]
791068-69-4 | [Synonyms]
Renin Substrate 1 trifluoroacetate salt | [Molecular Formula]
C109H156N32O21S | [MDL Number]
MFCD00284486 (net) | [MOL File]
791068-69-4.mol | [Molecular Weight]
2282.67 |
| Hazard Information | Back Directory | [Description]
The renin fluorogenic substrate consists of the normal peptide substrate for renin which has been linked to the fluorophore EDANS at one end and to a non-fluorescent quenching molecule (Dabcyl) at the other. After cleavage by renin, the product (peptide-EDANS) is brightly fluorescent and can be easily analyzed using an excitation wavelength of 340 nm and emission wavelengths of 485-510 nm. | [Uses]
Renin substrate 1 is a renin substrate with high affinity to the enzyme[1]. | [References]
[1] Paschalidou K, et al. Highly sensitive intramolecularly quenched fluorogenic substrates for renin based on the combination of L-2-amino-3-(7-methoxy-4-coumaryl)propionic acid with 2,4-dinitrophenyl groups at various positions. Biochem J. 2004 Sep 15;382(Pt 3):1031-8. DOI:10.1042/BJ20040729 |
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