| Identification | Back Directory | [Name]
Benzeneacetamide, N-(3-hydroxyphenyl)-4-methoxy- | [CAS]
791840-86-3 | [Synonyms]
NLRP3/AIM2-IN-2
Benzeneacetamide, N-(3-hydroxyphenyl)-4-methoxy- | [Molecular Formula]
C15H15NO3 | [MOL File]
791840-86-3.mol | [Molecular Weight]
257.28 |
| Chemical Properties | Back Directory | [Boiling point ]
514.8±40.0 °C(Predicted) | [density ]
1.251±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
9.54±0.10(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
NLRP3/aim2-in-2 (compound 8) is a new potent inhibitor with different species-specific effects on NLRP3 and AIM2 inflammasome dependent cell death. Its < b > IC < sub > 50 < / sub > < / b > value is 0.2392 μ M。 | [IC 50]
NLRP3 and AIM2: 0.2392±0.0 μM (IC50) | [References]
[1] Jiao Y, et al. Discovery of a novel and potent inhibitor with differential species-specific effects against NLRP3 and AIM2 inflammasome-dependent pyroptosis. Eur J Med Chem. 2022 Feb 11;232:114194. DOI:10.1016/j.ejmech.2022.114194 |
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