| Identification | Back Directory | [Name]
MAST CELL DEGRANULATING PEPTIDE HR-2 | [CAS]
80388-04-1 | [Synonyms]
HR 2
MCD PEPTIDE HR-2
MAST CELL DEGRANULATING PEPTIDE HR-2
MAST CELL DEGRANULATING (MCD) PEPTIDE HR-2
PHE-LEU-PRO-LEU-ILE-LEU-GLY-LYS-LEU-VAL-LYS-GLY-LEU-LEU-NH2
H-PHE-LEU-PRO-LEU-ILE-LEU-GLY-LYS-LEU-VAL-LYS-GLY-LEU-LEU-NH2
PHE-LEU-PRO-LEU-ILE-LEU-GLY-LYS-LEU-VAL-LYS-GLY-LEU-LEU-NH2: FLPLILGKLVKGLL-NH2
L-Leucinamide, L-phenylalanyl-L-leucyl-L-prolyl-L-leucyl-L-isoleucyl-L-leucylglycyl-L-lysyl-L-leucyl-L-valyl-L-lysylglycyl-L-leucyl- | [Molecular Formula]
C77H135N17O14 | [MDL Number]
MFCD00133527 | [MOL File]
80388-04-1.mol | [Molecular Weight]
1523 |
| Chemical Properties | Back Directory | [Boiling point ]
1631.5±65.0 °C(Predicted) | [density ]
1.139±0.06 g/cm3(Predicted) | [storage temp. ]
−20°C
| [pka]
13.41±0.46(Predicted) | [Sequence]
Phe-Leu-Pro-Leu-Ile-Leu-Gly-Lys-Leu-Val-Lys-Gly-Leu-Leu-NH2 |
| Hazard Information | Back Directory | [Uses]
Mast Cell Degranulating Peptide HR-2, a 14-membered linear peptide isolated from the venom of the giant hornet Vespa orientalis, is capable of degranulating mast cells and thus initiating histamine release[1]. | [References]
[1] Tu?chibaev MU, et al. [Low molecular weight peptides from the venom of the giant hornet Vespa orientalis. Structureand function]. Biokhimiia. 1988 Feb;53(2):219-26. PMID:2453223 |
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