| Identification | Back Directory | [Name]
EPOSTANE | [CAS]
80471-63-2 | [Synonyms]
Epostan
EPOSTANE
Win-32729
EPOSTANE USP/EP/BP
4α,5-Epoxy-3,17β-dihydroxy-4,17-dimethyl-5α-androst-2-ene-2-carbonitrile
(4α，5α，17β)-4，5-Epoxy-3，17-dihydroxy-4，17-dimethylandrost-2-ene-2-carbonitrile
Androst-2-ene-2-carbonitrile, 4,5-epoxy-3,17-dihydroxy-4,17-dimethyl-, (4α,5α,17β)- | [Molecular Formula]
C22H31NO3 | [MDL Number]
MFCD00199296 | [MOL File]
80471-63-2.mol | [Molecular Weight]
357.49 |
| Chemical Properties | Back Directory | [Melting point ]
191-194° | [alpha ]
D25 +67.4° (c = 1 in pyridine) | [Boiling point ]
490.1°C (rough estimate) | [density ]
1.1022 (rough estimate) | [refractive index ]
1.5614 (estimate) | [storage temp. ]
-20°C Freezer | [solubility ]
Chloroform (Slightly), Methanol (Slightly), Pyridine (Slightly) | [form ]
Solid | [pka]
8.59±0.70(Predicted) | [color ]
White to Off-White |
| Hazard Information | Back Directory | [Chemical Properties]
White to Off-White Solid | [Uses]
3β-Hydroxysteroid dehydrogenase inhibitor; a derivative of trilostane. Interceptive. | [in vivo]
Epostane (0-200 mg/kg, p.o., single dose) inhibits ovulation in mature rats and gonadotropin-stimulated ovulation in immature rats, terminates pregnancy through lowering plasma progesterone levels[1]. | Animal Model: | Sprague Dawley rats model[1] | | Dosage: | 0-200 mg/kg | | Administration: | p.o., single dose | | Result: | Terminated ovulation and pregnancy in rats, which was reversed by injections of progesterone. |
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| Company Name: |
J & K SCIENTIFIC LTD.
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| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
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