ChemicalBook--->CAS DataBase List--->8063-24-9

8063-24-9

8063-24-9 Structure

8063-24-9 Structure
IdentificationBack Directory
[Name]

Acriflavine hydrochloride
[CAS]

8063-24-9
[Synonyms]

CI 46000
EUFLAVINE
Acrifiavine
TRYPAFLAVINE
ACRIFLAVINE HCL
PALCAM SUPPLEMENT
acriflavinium chloride
EUFLAVIN HYDROCHLORIDE
acriflavinhydrochloride
ACRIFLAVINE HYDROCHLORIDE
AcriflavinForBiochemistry
Trypaflavine hydrochloride
ACRIFLAVINE.HCLRESEARCH GRADE
Acriflavine Hydrochloride 
ACID ACRIFLAVINE HYDROCHLORIDE
Acriflavine Hydrochloride (>90%)
LISTERIA SELECTIVE SUPPLEMENT UVM-II
LISTERIA PALCAM SELECTIVE SUPPLEMENT
PALCAM-LISTERIA SELECTIVE SUPPLEMENT
Acriflavine hydrochloride, 23-24.5% chloride
ACRIFLAVINE HYDROCHLORIDE, FOR FLUOR-ESC ENCE
3,6-DIAMINO-10-METHYLACRIDINIUM CHLORIDE HYDROCHLORIDE
3,6-Diamino-10-methylacridinium chloride hydrochloride, Euflavine
Acriflavine DiHCl (Mixture of AcriflaviniuM Chloride with Proflavine)
Acriflavine hydrochloride, Intercalating dye, antiseptic, analysis of cellular DNA and protein
(Mixture of 3,6-DiaMino-10-MethylacridiniuM Chloride Hydrochloride and 3,6-DiaMinoacridine Hydrochloride)
Acriflavine Hydrochloride (mixture of 3,6-Diamino-10-methylacridinium Chloride Hydrochloride and 3,6-Diaminoacridine Hydrochloride)
[EINECS(EC#)]

1312995-182-4
[Molecular Formula]

C27H28Cl4N6
[MDL Number]

MFCD00069039
[MOL File]

8063-24-9.mol
[Molecular Weight]

578.36
Chemical PropertiesBack Directory
[Appearance]

reddish-brown crystalline powder
[Melting point ]

260 °C
[storage temp. ]

+2°C TO
[solubility ]

H2O: soluble1mg/mL
[form ]

Powder
[color ]

Red-brown
[PH Range]

2
[Stability:]

Stable. Incompatible with strong oxidizing agents.
[Water Solubility ]

Soluble in water, dimethyl sulfoxide and methanol.
[Merck ]

123
[BRN ]

6265525
[Major Application]

diagnostic assay manufacturing
hematology
histology
[InChIKey]

VWXAJKFSYJFBIW-UHFFFAOYSA-N
[SMILES]

C12C=C(N)C=CC=1C=C1C=CC(N)=CC1=[N+]2C.C12C=C(C=CC1=CC1C=CC(N)=CC=1N=2)N.Cl.Cl.Cl.[Cl-]
Hazard InformationBack Directory
[Chemical Properties]

reddish-brown crystalline powder
[Uses]

Acriflavine is an topical antiseptic agent and has also been used for the treatment of external fungal infections.
[Biological Activity]

Acriflavine hydrochloride is a fluorescent dye. It is used as a topical contrast agent. It mainly stains nuclei and is applied to tissues before microscopy.
[Purification Methods]

Purify it by dissolving in 50 parts of H2O, shaking with a small excess of freshly precipitated and washed Ag2O. The mixture is set aside overnight at 0o and filtered. The cake is not washed. The pH of the filtrate is adjusted to 7.0 with HCl and evaporated to dryness. The residue is then crystallised twice from MeOH, twice from H2O and dried at 120o. at 452nm has a log value of 4.67. Itis ared max powder which readily absorbs H2O. The solubility is increased in the presence of proflavin. The dihydrochloride is a deep red crystalline powder. It is available as a mixture of 3,6-diaminoacridinium chloride (35%) and its 10-metho-chloride (65%). [See Albert, The Acridines Arnold Press p 346 1966, Benda Chem Ber 45 1787 1912]. [Beilstein 23 I 650.]
Safety DataBack Directory
[Hazard Codes ]

N-Xn,N,Xn
[Risk Statements ]

51/53-41-22-20/21/22
[Safety Statements ]

61-39-29-26-36
[RIDADR ]

UN 3077 9/PG 3
[WGK Germany ]

2
[HazardClass ]

9
[PackingGroup ]

III
[HS Code ]

38249064
[Storage Class]

11 - Combustible Solids
[Hazard Classifications]

Acute Tox. 4 Oral
Aquatic Chronic 2
Eye Dam. 1
Spectrum DetailBack Directory
[Spectrum Detail]

Acriflavine hydrochloride(8063-24-9)IR1
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