| Identification | Back Directory | [Name]
N-Acetyl-beta-alanyl-L-histidyl-L-seryl-L-histidine | [CAS]
820959-17-9 | [Synonyms]
Depuffin
tetrapeptide
Acetyl Tetrapeptide
Ac-β-Ala-His-Ser-His
Acetyl tetrapeptide-5
Tetrapeptide /Eyeseryl
Ac-βAla-His-Ser-His-OH
N-Ac-β-Ala-His-Ser-His
Eyeseryl WIPO、? Eyeseryl
Ac-Beta-Ala-His-Ser-His-OH
Acetyl tetrapeptide-5 powder
Depuffin/Acetyl Tetrapeptide-5
Acetyl Tetrapeptide-5/eyeseryl
Eyeseryl / Acetyl Tetrapeptide-5
Acetyl tetrapeptide-5 (eye serine peptide)
L-Histidine, N-acetyl-β-alanyl-L-histidyl-L-seryl-
N-Acetyl-beta-alanyl-L-histidyl-L-seryl-L-histidine
N-Acetyl-beta-alanyl-L-histidyl-L-seryl-L-histidine USP/EP/BP
CAS 820959-17-9 N-Acetyl-beta-alanyl-L-histidyl-L-seryl-L-histidine
Factory Directly Supply Cosmetics Material Acetyl Tetrapeptide-5 CAS No: 820959-17-9
(2S)-2-[[(2S)-2-[[(2S)-2-(3-acetamidopropanoylamino)-3-(1H-imidazol-5-yl)propanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-imidazol-5-yl)propanoic acid | [EINECS(EC#)]
1312995-182-4 | [Molecular Formula]
C20H28N8O7 | [MDL Number]
MFCD30179524 | [MOL File]
820959-17-9.mol | [Molecular Weight]
492.49 |
| Chemical Properties | Back Directory | [Boiling point ]
1237.3±65.0 °C(Predicted) | [density ]
1.443 | [storage temp. ]
Sealed in dry,2-8°C | [solubility ]
PBS (pH 7.2): 10 mg/ml | [form ]
A crystalline solid | [pka]
2.76±0.10(Predicted) | [InChIKey]
RIUMNDWYYDHBFO-UDJPXWLSNA-N | [SMILES]
C(O)(=O)[C@H](CC1N=CN=C1)NC(=O)[C@H](CO)NC(=O)[C@H](CC1N=CN=C1)NC(=O)CCNC(C)=O |&1:3,13,19,r| |
| Hazard Information | Back Directory | [Chemical Properties]
Acetyl Tetrapeptide-5 is a white to cream coloured powder. The active ingredient is used to treat lachrymal sacs and dark circles under the eyes. It stimulates cell metabolism, improves skin elasticity, reduces puffiness and water retention in the eye area and makes the skin supple.? | [Characteristics]
Acetyl tetrapeptide-5 inhibits collagen glycation avoiding skin losing elasticity and subsequent eyebags formation .
Acetyl tetrapeptide-5 prevents liquid accumulation in eyebags .
Acetyl tetrapeptide-5 shows a slight lightening effect which decreases dark circles under the eyes Use level: 0.01 %, maximum 0.1 % (water soluble) | [Uses]
anti-wrikle | [Application]
Acetyl tetrapeptisde-5 is a known humectant or hydroscopic moisturizer which helps reduce eye puffiness, improve skin elasticity and overall smoothness. | [Definition]
Acetyl Tetrapeptide-5(820959-17-9) is a synthetic peptide that has calming, smoothing, hydrating, and firmness-enhancing benefits when applied to skin. Its calming properties are believed to reduce undereye puffiness due to fluid accumulation, such as from allergies (which is not the same as undereye bags that occur from fat pads beneath the skin slipping out of place).
| [benefits]
Acetyl tetrapeptide-5 is an acetyl oligopeptide whose role is to inhibit collagen glycation and increase vascular permeability in a dose-dependent manner. This prevents liquid accumulation under the eyes and decreases eye puffiness, as well as improving skin elasticity. Two studies showed that acetyl tetrapeptide-5 reduced under-eye puffiness and discoloration. | [Safety]
Some humectants may be irritants at extremely high concentrations, but acetyl tetrapeptide-5 is generally considered non-hazardous to the body and the environment by the cosmetics database.
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