| Identification | Back Directory | [Name]
N2-Acetyl-L-lysylglycyl-L-histidyl-L-lysinamide | [CAS]
827306-88-7 | [Synonyms]
capixyl
Ac-KGHK
Ac-Lys-Gly-His-Lys
Acetyl Tetrapeptide-3
acetyl tetrapeptide-3/capixyl
Acetyl Tetrapeptide-4, Capixyl
Acetyl Tetrapeptide-3/Capixyl-3
N2-Acetyl-L-lysylglycyl-L-histidyl-L-lysinamide
L-Lysinamide, N2-acetyl-L-lysylglycyl-L-histidyl- | [EINECS(EC#)]
1308068-626-2 | [Molecular Formula]
C22H39N9O5 | [MDL Number]
MFCD31715096 | [MOL File]
827306-88-7.mol | [Molecular Weight]
509.6 |
| Chemical Properties | Back Directory | [Boiling point ]
1075.4±65.0 °C(Predicted) | [density ]
1.250±0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C | [solubility ]
DMF: 14 mg/ml DMSO: 10 mg/ml Ethanol: 10 mg/ml PBS (pH 7.2): 10 mg/ml | [form ]
A solid | [pka]
13.35±0.46(Predicted) | [InChIKey]
RRJOMESUBQAYOA-BZSNNMDCSA-N | [SMILES]
C(N)(=O)[C@H](CCCCN)NC(=O)[C@H](CC1N=CNC=1)NC(=O)CNC(=O)[C@H](CCCCN)NC(C)=O |
| Hazard Information | Back Directory | [Description]
Acetyl tetrapeptide-3 is a biomimetic peptide. It increases protein levels of type III collagen and total laminins in MRC5 human fibroblasts when used at a concentration of 1 μM. Acetyl tetrapeptide-3 reverses corticoid-induced decreases in collagen VII expression at the dermal-epidermal junction in human skin explants. | [Uses]
Acetyl tetrapeptide-3 stimulates hair growth with higher activity than the reference hair growth product, Minoxidil. This can help to anchor the hair fibre into the scalp which can strengthen strands and target the causes of hair loss. By combining this ingredient with Red Clover Extract, the benefits can be accelerated helping to improve blood circulation to the roots, increasing thickness and hair volume. | [benefits]
Acetyl Tetrapeptide-3 Stimulate fibroblast around dermal follicle toproduce matrix protein( collagen lll, laminin.etc.)and collagen VlI, fill the hair follicle, boost hairgrowth. Its recommended dosage is 1~5%. | [Biological Functions]
Acetyl tetrapeptide-3 is a biomimetic peptide. It increases protein levels of type III collagen and total laminins in MRC5 human fibroblasts when used at a concentration of 1 μM. Acetyl tetrapeptide-3 reverses corticoid-induced decreases in collagen VII expression at the dermal-epidermal junction in human skin explants. |
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