| Identification | More | [Name]
1,4-Dichloro-2-butyne | [CAS]
821-10-3 | [Synonyms]
1,4-DICHLORO-2-BUTYNE
1,4-dichloro-2-butyn
1,4-dichloro-but-2-yne
1,4-Dichlorobutyne
Dichlorobutyne
2-Butyne, 1,4-dichloro-
bis(chloromethyl)acetylene | [EINECS(EC#)]
212-474-8 | [Molecular Formula]
C4H4Cl2 | [MDL Number]
MFCD00000981 | [Molecular Weight]
122.98 | [MOL File]
821-10-3.mol |
| Safety Data | Back Directory | [Symbol(GHS) ]
 
GHS06,GHS07 | [Signal word ]
Warning | [Hazard statements ]
H301-H315-H319-H335 | [Precautionary statements ]
P261-P305+P351+P338-P264-P270-P280-P301+P310+P330-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P405-P501 | [Hazard Codes ]
Xi,T | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin .
R40:Limited evidence of a carcinogenic effect.
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S38:In case of insufficient ventilation, wear suitable respiratory equipment .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . | [RIDADR ]
UN 2810 | [WGK Germany ]
3
| [RTECS ]
ER9600000
| [F ]
8-10 | [TSCA ]
TSCA listed | [HazardClass ]
6.1 | [PackingGroup ]
II | [HS Code ]
29032900 | [Safety Profile]
Poison by intravenous
route. When heated to decomposition it
emits toxic fumes of Cl-. Probably a
dangerous fKe and explosion hazard. See
also ACETYLENE COMPOUNDS and
CHLORINATED HYDROCARBONS,
ALIPHATIC |
| Hazard Information | Back Directory | [Chemical Properties]
CLEAR COLORLESS TO YELLOWISH LIQUID | [Uses]
1,4-Dichloro-2-butyne used in the synthesis of 1,4-disubstituted 1,2,3-triazoles. Also, it is used in the approach of the 20S-camptothecin family of antitumor agents. | [Preparation]
1,4-Dichloro-2-butyne could be conveniently prepared by treating 1,4-butynediol with Thionyl Chloride. However, as a precautionary measure, the medium is diluted with CH2Cl2 and cooled to ?30?°C before adding thionyl chloride to avoid hazards associated with the exothermicity of the reaction.
| [Reactions]
1,4-Dichloro-2-butyne can be converted into other compounds such as amides, ethers, and esters using ethyl diazoacetate. |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
| Company Name: |
Maya High Purity Chemicals
|
| Telephone: |
+86 (573) 82222445 (0)18006601000 452520369 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList15221/0_EN.htm |
| Company Name: |
T&W GROUP
|
| Telephone: |
021-61551611 13296011611 |
| Website: |
www.trustwe.com/ |
|