| Identification | Back Directory | [Name]
2OH-BNPP1 | [CAS]
833481-73-5 | [Synonyms]
2OH-BNPP1
2-((4-Amino-1-(tert-butyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl)methyl)phenol
Phenol, 2-[[4-amino-1-(1,1-dimethylethyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl]methyl]- | [Molecular Formula]
C16H19N5O | [MDL Number]
MFCD28120704 | [MOL File]
833481-73-5.mol | [Molecular Weight]
297.36 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : ≥ 100 mg/mL (336.30 mM) | [form ]
Solid | [color ]
White to off-white | [InChI]
InChI=1S/C16H19N5O/c1-16(2,3)21-15-13(14(17)18-9-19-15)11(20-21)8-10-6-4-5-7-12(10)22/h4-7,9,22H,8H2,1-3H3,(H2,17,18,19) | [InChIKey]
LWLCFWPPMNPMOI-UHFFFAOYSA-N | [SMILES]
C1(O)=CC=CC=C1CC1C2=C(N)N=CN=C2N(C(C)(C)C)N=1 |
| Hazard Information | Back Directory | [Uses]
2OH-BNPP1 is a novel inhibitor of checkpoint kinase BUB1. | [in vivo]
2OH-BNPP1 (50 mg/kg) blocks TGFβ signaling in vivo, and significantly decreases abundance of phosphorylated SMAD2 in tumor-bearing mice[1]. | [storage]
Store at -20°C |
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| Company Name: |
ChemeGen
|
| Telephone: |
18818260767 |
| Website: |
https://www.chemegen.com |
|