| Identification | More | [Name]
1-(5-ISOQUINOLINESULFONYL)PIPERAZINE, DIHYDROCHLORIDE | [CAS]
84468-24-6 | [Synonyms]
1-(5-ISOQUINOLINESULFONYL)PIPERAZINE
1-(5-ISOQUINOLINESULFONYL)PIPERAZINE, DIHYDROCHLORIDE
1-(5-ISOQUINOLINYLSULFONYL)PIPERAZINE 2HCL
1-(5-ISOQUINOLINYLSULFONYL)-PIPERAZINE HYDROCHLORIDE
C-1
HA-100
HA-100 DIHYDROCHLORIDE
HA-100 HYDROCHLORIDE
1-(5-isoquinolinylsulfonyl)-piperazin
1-(5-isoquinolinylsulfonyl)piperazine
1-(5-isoquinolinesulfonyl)piperazine hydrochloride
1-[(Isoquinolin-5-yl)sulfonyl]piperazine
IQSP | [Molecular Formula]
C13H17Cl2N3O2S | [MDL Number]
MFCD01310980 | [Molecular Weight]
350.26 | [MOL File]
84468-24-6.mol |
| Chemical Properties | Back Directory | [Appearance]
Pale Yellow Crystalline Solid | [Melting point ]
>240°C (dec.) | [Boiling point ]
497.4±55.0 °C(Predicted) | [density ]
1.332±0.06 g/cm3(Predicted) | [storage temp. ]
−20°C
| [solubility ]
DMSO, Methanol, Water | [form ]
Off-white lyophilized solid. | [pka]
7.66±0.10(Predicted) | [color ]
Off-White to Pale Yellow | [Usage]
Exhibited potent inhibition toward protein kinase C and cyclic nucleotide dependent protein kinases | [InChI]
1S/C13H15N3O2S.2ClH/c17-19(18,16-8-6-14-7-9-16)13-3-1-2-11-10-15-5-4-12(11)13;;/h1-5,10,14H,6-9H2;2*1H | [InChIKey]
ZKQAPKKKTQCVKG-UHFFFAOYSA-N | [SMILES]
[H]Cl.[H]Cl.O=S(C1=CC=CC2=C1C=CN=C2)(N3CCNCC3)=O | [CAS DataBase Reference]
84468-24-6(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [RTECS ]
TM0862600
| [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral |
| Hazard Information | Back Directory | [Chemical Properties]
Pale Yellow Crystalline Solid | [Uses]
Exhibited potent inhibition toward protein kinase C and cyclic nucleotide dependent protein kinases | [Definition]
ChEBI: 5-(1-piperazinylsulfonyl)isoquinoline is a member of isoquinolines. | [Biological Activity]
Inhibitor of protein kinase C. Vasodilator. | [IC 50]
PKC: 12 μM (IC50); PKG: 4 μM (IC50); PKA: 8 μM (IC50); MLCK: 240 μM (IC50); PKC: 6.5 μM (Ki); MLCK: 61 μM (Ki) |
|
| Company Name: |
BOC Sciences
|
| Tel: |
1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
| Company Name: |
Twochem Co.Ltd.
|
| Tel: |
021-58111628 15800915896 |
| Website: |
cn.twochem.com |
|