ChemicalBook--->CAS DataBase List--->85073-19-4

85073-19-4

85073-19-4 Structure

85073-19-4 Structure
IdentificationBack Directory
[Name]

lithium phenyl-2,4,6-trimethylbenzoylphosphinate
[CAS]

85073-19-4
[Synonyms]

photoinitiator LAP
Lithium PTMB phosphinate
lithium phenyl-2,4,6-trimethylbenzoylphosphinate
P-Phenyl-P-(2,4,6-trimethylbenzoyl)phosphinic acid
lithium phenyl-2,4,6-trimethylbenzoylphosphinate N
LAP (Lithium phenyl-2,4,6-trimethylbenzoylphosphinate)
OC2000, Lithium Phenyl(2,4,6-trimethylbenzoyl)phosphinate
Phenyl(2,4,6-trimethylbenzoyl)phosphinic Acid Lithium Salt
[Molecular Formula]

C16H16LiO3P
[MDL Number]

MFCD29472537
[MOL File]

85073-19-4.mol
[Molecular Weight]

296.23
Chemical PropertiesBack Directory
[storage temp. ]

2-8°C
[solubility ]

Soluble in DMSO
[form ]

crystalline powder
[color ]

white to off-white
[InChI]

InChI=1S/C16H17O3P.Li.H/c1-11-9-12(2)15(13(3)10-11)16(17)20(18,19)14-7-5-4-6-8-14;;/h4-10H,1-3H3,(H,18,19);;
[InChIKey]

CVDUWYDMNPODNA-UHFFFAOYSA-N
[SMILES]

C(C1C(=CC(C)=CC=1C)C)(=O)P(C1C=CC=CC=1)(O)=O.[LiH]
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P280-P301+P312-P302+P352-P305+P351+P338
[WGK Germany ]

WGK 3
[HS Code ]

2931499090
[Storage Class]

11 - Combustible Solids
Hazard InformationBack Directory
[Description]

LAP (Lithium phenyl-2,4,6-trimethylbenzoylphosphinate) is a free radical initiator. The free radicals produced by LAP under bioprinting conditions are potentially cytotoxic and mutagenic. In addition, the concentration of LAP affects the mechanical strength of 3D-printed scaffolds. Generally, the concentration range of LAP used for curing is 0.05%-1%. The elastic modulus produced at a concentration of 0.1% is the highest, with enhanced mechanical properties and excellent biocompatibility.
[Chemical Properties]

White to off-white powder with excellent water solubility and good cellular compatibility; A blue light photoinitiator capable of rapidly initiating the curing of photosensitive hydrogel materials under blue light (wavelength 405 nm). Suitable for long-wavelength water-based photocurable coatings, water-based photocurable inks, water-based photocurable 3D printing, the curing of hydrogels containing cells, and bio-3D printing involving cells.
[Uses]

Lithium phenyl-2,4,6-trimethylbenzoylphosphinate (LAP) is a water soluble, cytocompatible, Type I photoinitiator for use in the polymerization of hydrogels or other polymeric materials. This photoinitator is preferred over Irgacure 2959 for biological applications due to its increased water solubility, increased polymerization rates with 365 nm light, and absorbance at 400 nm allowing for polymerization with visible light. The improved polymerization kinetics enable cell encapsualation at reduced initiator concentration and longer wavelength light, which has been shown to reduce initiator toxicity and increase cell viability.
[storage]

Store at -20°C
Spectrum DetailBack Directory
[Spectrum Detail]

lithium phenyl-2,4,6-trimethylbenzoylphosphinate(85073-19-4)FT-IR
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