| Identification | Back Directory | [Name]
O-Pyruvoylsalicylic acid hydrate | [CAS]
856095-68-6 | [Synonyms]
OBA-09
OBA-09 hydrate
O-Pyruvoylsalicylic acid hydrate
2-(1,2-dioxopropoxy)-Benzoic acid9
Benzoic acid, 2-(1,2-dioxopropoxy)-
2-(1,2-Dioxopropoxy)benzoic acid hydrate | [Molecular Formula]
C10H8O5 | [MDL Number]
MFCD20488062 | [MOL File]
856095-68-6.mol | [Molecular Weight]
208.17 |
| Hazard Information | Back Directory | [Description]
OBA-09 is an ester of pyruvate and salicylic acid that has neuroprotective properties.1 It decreases lactate dehydrogenase (LDH) release and prevents cell death induced by NMDA or zinc, and reduces the production of reactive oxygen species (ROS) induced by oxygen-glucose deprivation in mixed rat primary cortical cells when used at concentrations of 10 and 15 mM. OBA-09 (10 mg/kg) reduces infarct volume by 89.9% and decreases expression of IL-1β, inducible nitric oxide synthase (iNOS), COX-2, and TNF-α in the brain in a rat model of ischemia induced by middle cerebral artery occlusion (MCAO).1,2 It improves motor performance in the rotarod test in the same model when administered at a dose of 10 mg/kg.1WARNING This product is not for human or veterinary use. |
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| Company Name: |
Musechem
|
| Tel: |
+1-800-259-7612 |
| Website: |
www.musechem.com |
| Company Name: |
InvivoChem
|
| Tel: |
13549236410 |
| Website: |
https://www.invivochem.cn/ |
|