Identification | Back Directory | [Name]
AMG-628 | [CAS]
862269-73-6 | [Synonyms]
AMG-628 CHEMBL226574 UNII-28J966TN3X Acetamide, N-[4-[[6-[4-[1-(4-fluorophenyl)ethyl]-1-piperazinyl]-4-pyrimidinyl]oxy]-2-benzothiazolyl]- | [Molecular Formula]
C25H25FN6O2S | [MOL File]
862269-73-6.mol | [Molecular Weight]
492.57 |
Hazard Information | Back Directory | [Uses]
(Rac)-AMG 628 is the racemate of AMG 628, a potent TRPV1 antagonist with an IC50 of 3.7nM. AMG 628 can be used in chronic pain research[1]. | [References]
[1] Thiel OR, et al. Practical synthesis of a vanilloid receptor-1 antagonist. J Org Chem. 2008 May 2;73(9):3508-15. DOI:10.1021/jo8002216 |
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