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862269-73-6

862269-73-6 Structure

862269-73-6 Structure
IdentificationBack Directory
[Name]

AMG-628
[CAS]

862269-73-6
[Synonyms]

AMG-628
CHEMBL226574
UNII-28J966TN3X
Acetamide, N-[4-[[6-[4-[1-(4-fluorophenyl)ethyl]-1-piperazinyl]-4-pyrimidinyl]oxy]-2-benzothiazolyl]-
[Molecular Formula]

C25H25FN6O2S
[MOL File]

862269-73-6.mol
[Molecular Weight]

492.57
Hazard InformationBack Directory
[Uses]

(Rac)-AMG 628 is the racemate of AMG 628, a potent TRPV1 antagonist with an IC50 of 3.7nM. AMG 628 can be used in chronic pain research[1].
[References]

[1] Thiel OR, et al. Practical synthesis of a vanilloid receptor-1 antagonist. J Org Chem. 2008 May 2;73(9):3508-15. DOI:10.1021/jo8002216
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