ChemicalBook--->CAS DataBase List--->472981-92-3

472981-92-3

472981-92-3 Structure

472981-92-3 Structure
IdentificationBack Directory
[Name]

4'-CHLORO-3-METHOXYCINNAMANILIDE
[CAS]

472981-92-3
[Molecular Formula]

C16H14ClNO2
[MDL Number]

MFCD01033818
[MOL File]

472981-92-3.mol
[Molecular Weight]

287.74
Chemical PropertiesBack Directory
[Melting point ]

165-167℃
[storage temp. ]

Store at RT
[solubility ]

DMSO: 13 mg/mL, soluble
[form ]

solid
[color ]

off-white
Safety DataBack Directory
[Safety Statements ]

22-24/25
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

A potent and selective vanilloid receptor (TRPV1) antagonist. An effective antagonist of hTRPV1 when stimulated by capsaicin, acid, or noxious heat.
[Biological Activity]

Potent, selective and competitive vanilloid TRPV1 (VR1) receptor antagonist (pA 2 = 7.71 at hVR1); antagonizes hTRPV1 receptors activated by agonists, noxious heat, but not protons. Displays selectivity over a wide range of receptors and systems including CB 1 and CB 2 receptors, voltage-gated Ca 2+ channels and the hyperpolarization-activated current (I h ). Also available as part of the Vanilloid TRPV1 Receptor Tocriset™ .
Spectrum DetailBack Directory
[Spectrum Detail]

4'-CHLORO-3-METHOXYCINNAMANILIDE(472981-92-3)1HNMR
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