| Identification | Back Directory | [Name]
FMOC-12-AMINO-4,7,10-TRIOXADODECANOIC ACID | [CAS]
867062-95-1 | [Synonyms]
Fmoc-PEG3- CH2CH2COOH
Fmoc-N-amido-PEG3-acid
FMoc-NH-PEG3-CH2CH2COOH
Fmoc-PEG3-propionic acid
FMOC-12-AMINO-4,7,10-TRIOXADODECANOIC ACID
N-Fmoc-12-amino-4,7,10-trioxadodecanoic acid
12-(Fmoc-amino)-4,7,10-trioxadodecanoic Acid
1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13-tetraoxa-4-azahexadecan-16-oic acid
5,8,11-Trioxa-2-azatetradecanedioic acid, 1-(9H-fluoren-9-ylmethyl) ester
Fmoc-PEG3-OH
1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13-tetraoxa-4-azahexadecan-16-oic acid
2-[2-[2-(2-aminoethoxy)ethoxy]ethoxymethyl]-3-(9H-fluoren-9-ylmethoxy)-3-oxopropanoic acid | [Molecular Formula]
C24H29NO7 | [MDL Number]
MFCD06656471 | [MOL File]
867062-95-1.mol | [Molecular Weight]
443.49 |
| Chemical Properties | Back Directory | [Melting point ]
43-46°C | [Boiling point ]
651.9±55.0 °C(Predicted) | [density ]
1.230 | [storage temp. ]
Sealed in dry,2-8°C | [solubility ]
DMSO (Sparingly), Methanol (Slightly) | [form ]
Solid | [pka]
4.28±0.10(Predicted) | [color ]
White | [Major Application]
peptide synthesis | [InChI]
InChI=1S/C24H29NO7/c26-23(27)9-11-29-13-15-31-16-14-30-12-10-25-24(28)32-17-22-20-7-3-1-5-18(20)19-6-2-4-8-21(19)22/h1-8,22H,9-17H2,(H,25,28)(H,26,27) | [InChIKey]
CHIDDYZONKDHLG-UHFFFAOYSA-N | [SMILES]
C(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)(=O)NCCOCCOCCOCCC(O)=O |
| Hazard Information | Back Directory | [Description]
Fmoc-N-amido-PEG3-acid is a PEG linker containing an Fmoc-protected amine and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. | [Chemical Properties]
White powder | [Uses]
1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13-tetraoxa-4-azahexadecan-16-oic Acid has been used as a reactant for the preparation of vaccines. | [reaction suitability]
reaction type: Pegylations | [IC 50]
Cleavable Linker; PEGs |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
T&W GROUP
|
| Telephone: |
021-61551611 13296011611 |
| Website: |
www.trustwe.com/ |
|