| Chemical Properties | Back Directory | [Boiling point ]
699.1±50.0 °C(Predicted) | [density ]
1.084±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20 °C | [pka]
8.74±0.10(Predicted) | [Appearance]
white semi solid |
| Hazard Information | Back Directory | [Uses]
m-PEG16-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [Biological Activity]
m-PEG16-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | [IC 50]
PEGs | [References]
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
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T&W GROUP
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021-61551611 13296011611 |
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www.trustwe.com/ |
| Company Name: |
Henan Alfachem Co.,Ltd.
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| Telephone: |
0371-55051623 18137891487 |
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www.chemicalbook.com/supplier/14555231/ |
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