| Identification | More | [Name]
Fluazuron | [CAS]
86811-58-7 | [Synonyms]
1-[4-Chloro-3-(3-chloro-5-trifluoromethyl-2-pyridyloxy)phenyl]-3-(2,6-difluorobenzoyl)urea
ACATAK
FLUAZURON
n-(((4-chloro-3-((3-chloro-5-(trifluoromethyl)-2-pyridinyl)oxy)phenyl)amino)carbonyl)-2,6-difluorobenzamide
1-(4-chklor-3-(3-chloro-5-trifluoromethyl-2-pyridyloxy)phenyl)-3-(2,6-difluorobenzoyl)urea
N-(4-chloro-3-3-chloro-5-(trifluoromethyl)-2-pyridinyl)oxy phenyl amino-2,6-difluorobenzamide
FLUAZURON PESTANAL, 100 MG
fluazuron (bsi, pa e-iso, inn)
4002 FLUAZURON
N-(((4-Chloro-3-((3-chloro-5-(trifluoromethyl)-2-pyridinyl)oxy)phenyl)amino)carbonyl)-2,6-difluorobenzamide | [EINECS(EC#)]
245-553-0 | [Molecular Formula]
C20H10Cl2F5N3O3 | [MDL Number]
MFCD00864505 | [Molecular Weight]
506.21 | [MOL File]
86811-58-7.mol |
| Chemical Properties | Back Directory | [Appearance]
White Powder | [Melting point ]
217-2190C | [density ]
1.579±0.06 g/cm3(Predicted) | [vapor pressure ]
1.2 x l0-7 mPa (20 °C) | [Fp ]
>200 °C | [storage temp. ]
0-6°C | [solubility ]
DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml | [form ]
neat | [pka]
8.61±0.46(Predicted) | [Water Solubility ]
＜0.02 mg l-1(20 °C) | [Usage]
A pesticide | [Major Application]
agriculture
environmental | [InChI]
1S/C20H10Cl2F5N3O3/c21-11-5-4-10(29-19(32)30-17(31)16-13(23)2-1-3-14(16)24)7-15(11)33-18-12(22)6-9(8-28-18)20(25,26)27/h1-8H,(H2,29,30,31,32) | [InChIKey]
YOWNVPAUWYHLQX-UHFFFAOYSA-N | [SMILES]
Fc1cccc(F)c1C(=O)NC(=O)Nc2ccc(Cl)c(Oc3ncc(cc3Cl)C(F)(F)F)c2 | [CAS DataBase Reference]
86811-58-7(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
N | [Risk Statements ]
R50/53:Very Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment . | [Safety Statements ]
S60:This material and/or its container must be disposed of as hazardous waste .
S61:Avoid release to the environment. Refer to special instructions safety data sheet . | [RIDADR ]
3077 | [WGK Germany ]
2 | [HazardClass ]
9 | [PackingGroup ]
III | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Aquatic Acute 1
Aquatic Chronic 1 |
| Hazard Information | Back Directory | [Chemical Properties]
White Powder | [Uses]
A pesticide, like other BPUs it interferes with chitin synthesis. | [Uses]
Fluazuron is used for the strategic control of the cattle tick Boaphilus
microplus on beef cattle. | [Definition]
ChEBI: Fluazuron is an N-acylurea that is urea in which one of the hydrogens has been replaced by a 3,6-difluorobenzoyl group, while a hydrogen attached to the other nitrogen has been replaced by a 4-chloro-3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl group. It is used to control ticks in cattle. It has a role as a mite growth regulator and an acaricide. It is an organofluorine acaricide, an organochlorine acaricide, a member of monochlorobenzenes, a N-acylurea, a chloropyridine, an aromatic ether and a member of phenylureas. | [Synthesis]
A method for chemically synthesizing fluazuron comprises the following steps of: subjecting 2-chloro-5-nitrophenol and 2,3-dichloro-5-methyl triflouro pyridine to an etherifying reaction to prepare etherate; reducing to generate 4-chloro-3-(3-chloro-5-methyl triflouro2-pyridyloxy) aniline by taking ethanol or methanol as solvents and sodium bisulfide as a reducing agent; subjecting 2,6-difluorobenzamide and triphosgene to an N-acylation reaction to obtain 2,6-difluorobenzoyl isocyanate; and subjecting 4-chloro-3-(3-chloro-5methyl triflouro2-pyridyloxy) aniline and the 2,6-difluorobenzoyl isocyanate to an addition reaction to prepare the fluazuron.1
| [Metabolic pathway]
Only limited information is available in the open literature on the
metabolism of fluazuron in animals. Based on its use, information on
metabolism in soils and plants is not relevant. | [Degradation]
Fluazuron is less stable at alkaline pH than under acidic conditions. The
hydrolysis DT50 at 25 °C was reported to be 14 days at pH 3, 7 days at
pH 5,20 hours at pH 7 and 0.5 hours at pH 9 (PM). | [References]
[1]CN101906070A
|
|
|