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878489-28-2

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878489-28-2 Structure

878489-28-2 Structure
IdentificationBack Directory
[Name]

2-(4-Chlorophenoxy)-2-methyl-N-[5-[(methylsulfonyl)amino]tricyclo[3.3.1.13,7]dec-2-yl]-propanamide
[CAS]

878489-28-2
[Synonyms]

JNJ 303
2-(4-Chlorophenoxy)-2-methyl-N-[5-[(methylsulfonyl)amino]tricyclo[3.3.1.13,7]dec-2-yl]-propanamide
Propanamide, 2-(4-chlorophenoxy)-2-methyl-N-[5-[(methylsulfonyl)amino]tricyclo[3.3.1.13,7]dec-2-yl]-, stereoisomer
[Molecular Formula]

C21H29ClN2O4S
[MOL File]

878489-28-2.mol
[Molecular Weight]

440.98
Chemical PropertiesBack Directory
[density ]

1.33±0.1 g/cm3(Predicted)
[storage temp. ]

Store at +4°C
[solubility ]

DMSO : 62.5 mg/mL (141.73 mM; Need ultrasonic)
[form ]

Powder
[pka]

10.63±0.40(Predicted)
[color ]

Light yellow to yellow
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
Hazard InformationBack Directory
[Uses]

JNJ 303 is an 11-beta hydroxysteroid dehydrogenase (11β-HSD1) inhibitor.
[in vivo]

JNJ 303 recapitulates the Exn4-induced decrease in fasting blood glucose level in mice[2].

[storage]

Store at -20°C
Spectrum DetailBack Directory
[Spectrum Detail]

2-(4-Chlorophenoxy)-2-methyl-N-[5-[(methylsulfonyl)amino]tricyclo[3.3.1.13,7]dec-2-yl]-propanamide(878489-28-2)1HNMR
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