| Identification | Back Directory | [Name]
O-(2-AMINOETHYL)-O-(2-(BOC-AMINO)ETHYL)OCTAETHYLENE GLYCOL | [CAS]
890091-43-7 | [Synonyms]
BOC-NH-PEG9-NH2
NHBoc-PEG9-amine
boc-peg-amine (n=9)
Boc-amido-PEG9-amine
BOC-N-AMIDO-PEG9-NH2
Boc-NH-PEG9-CH2CH2NH2
Boc-N-amido-PEG9-Amine
t-Boc-N-amido-PEG9-Amine
t-boc-N-amido-PEG10-amine
O-(2-AMinoethyl )-O`-[2-(Boc-aMino)ethyl ]octaaethylene glycol
tert-Butyl (29-amino-3,6,9,12,15,18,21,24,27-nonaoxanonacosyl)carbamate
2-Methyl-2-propanyl (29-amino-3,6,9,12,15,18,21,24,27-nonaoxanonacos-1-yl)carbamate
O-(2-Aminoethyl)-O'-[2-(Boc-amino)ethyl]octaethylene glycol >=90% (oligomer purity)
31-Amino-5,8,11,14,17,20,23,26,29-nonaoxa-2-azahentriacontanoic acid 1,1-dimethylethyl ester
5,8,11,14,17,20,23,26,29-Nonaoxa-2-azahentriacontanoicacid, 31-amino-, 1,1-dimethylethyl ester
tert-butyl N-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]carbamate | [Molecular Formula]
C25H52N2O11 | [MDL Number]
MFCD03453249 | [MOL File]
890091-43-7.mol | [Molecular Weight]
556.69 |
| Chemical Properties | Back Directory | [Boiling point ]
609.8±55.0 °C(Predicted) | [density ]
1.082±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
Soluble in Water, DMSO, DMF, DCM | [form ]
Liquid | [pka]
12.23±0.46(Predicted) | [color ]
Colorless to light yellow | [InChI]
InChI=1S/C25H52N2O11/c1-25(2,3)38-24(28)27-5-7-30-9-11-32-13-15-34-17-19-36-21-23-37-22-20-35-18-16-33-14-12-31-10-8-29-6-4-26/h4-23,26H2,1-3H3,(H,27,28) | [InChIKey]
RTTGVFBQUXJWJG-UHFFFAOYSA-N | [SMILES]
C(OC(C)(C)C)(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN |
| Hazard Information | Back Directory | [Description]
t-Boc-N-amido-PEG9-amine is a monodisperse PEG reagent containing an amino group and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The Boc group can be deprotected under mild acidic conditions to form the free amine. | [Uses]
Boc-amido-PEG9-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [General Description]
Our highly purified mono-protected homobifunctional polyethylene glycols display oligomer purities of more than 90%. This extremely narrow distribution of oligomers ensures homogeneous products in many applications such as conjugation reactions or introduction of solubilizing units or spacers. | [reaction suitability]
reagent type: cross-linking reagent | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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T&W GROUP
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| Company Name: |
Sigma-Aldrich
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https://www.sigmaaldrich.cn |
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