ChemicalBook--->CAS DataBase List--->9002-12-4

9002-12-4

9002-12-4 Structure

9002-12-4 Structure
IdentificationBack Directory
[Name]

URICASE
[CAS]

9002-12-4
[Synonyms]

UAO
URICASE
Uricozyme
EC 1.7.3.3
EC: 1.7.3.3
urikoxidase
Uratoxidase
Uric oxidase
IUB: 1.7.3.3
URATE OXIDASE
oxidase,urate
urico-oxidase
uricase type V
Uricaseexpigliver
Uric acid oxidase
URICASE, PIG LIVER
URICASE TYPE VIII-S
URICASE, RECOMBINANT
URATE: OXIDOREDUCTASE
uricase, bovine kidney
URICASE FROM PIG LIVER
Uricase [>=10 units/mg]
uricase from candida sp.
URATE: O2 OXIDOREDUCTASE
URATE: OXYGEN OXOREDUCTASE
uricase from porcine liver
Urate oxidase (from Yeast)
Uricase froM Candida utilis
URATE: OXYGEN OXIDOREDUCTASE
Uricase Bacillus fastidiosus
Uricase recombinant, lyophil.
UricaseExPigLiver(E.C.1.7.3.3)
Uricase from Bacillus fastidiosus
uricase from arthrobacter globiformis
Uricase, Urate: oxygen oxidoreductase
Urate oxidase, Urate:O2 oxidoreductase
URICASE TYPE X FROM CORYNEBACTERIUM SPEC IES
uricase microbial type vii from candida utilis
URICASE FROM BACILLUS SP., ACTIVITY: 4.0 UNITS/MG
URICASE TYPE II SOLUBLE POWDER FROM*BOVI NE KIDNEY
Uricase from Candida sp.,Urate: oxygen oxoreductase
uricase from bacillus fastidiosus lyoph. white powder
URICASE FROM CANDIDA UTILIS, ACTIVITY: LARGER THAN 3.0 UNITS/MG
Uricase from Arthrobacter globiformis,Urate oxidase, Urate:O2 oxidoreductase
[EINECS(EC#)]

232-655-5
[Molecular Formula]

NULL
[MDL Number]

MFCD00082126
[MOL File]

9002-12-4.mol
[Molecular Weight]

567.398
Chemical PropertiesBack Directory
[storage temp. ]

−20°C
[solubility ]

5 mg/mL, clear, colorless to very faintly yellow (in enzyme dilution buffer)
[form ]

lyophilized powder
[color ]

White to off-white
[biological source]

Bacillus sp. (B. fastidiosus)
[Water Solubility ]

Hardly soluble in water, slightly soluble in buffer alkaline solution.
[Merck ]

13,9944
[Specific Activity]

15-30units/mg protein (biuret)
[Major Application]

detection
[InChIKey]

VPXDHZMLJOJKOX-UHFFFAOYSA-N
[SMILES]

N.OCC1OC(C(O)C1OP(O)(=O)OCC2OC(C(O)C2O)N3C=CC(=O)NC3=O)N4C=CC(=O)NC4=O
[EPA Substance Registry System]

Oxidase, urate (9002-12-4)
Hazard InformationBack Directory
[Chemical Properties]

White powder
[Uses]

In the determination of serum and urine uric acid.
[Uses]

Uricase is very important for the determination of uric acid in biological fluids. Uricase is an important medical enzyme which can be used to determine urate in clinical analysis. The enzyme Urate oxidase (UO) catalyzes the oxidation of uric acid to 5-hydroxyisourate.
[General Description]

Mice deficient in uricase develop uric acid nephropathy and diabetes insipidus which can be mitigated with recombinant uricase treatment.
[Biochem/physiol Actions]

Uricase catalyzes the oxidation of uric acid to 5-hydroxyisourate, which subsequently forms (S)-allantoin. It is involved in purine metabolism, urate degradation and (S)-allantoin formation .
Safety DataBack Directory
[Symbol(GHS) ]

Health Hazard (GHS08)
GHS08
[Signal word ]

Danger
[Hazard statements ]

H319-H334-H360FD
[Precautionary statements ]

P202-P261-P264-P280-P305+P351+P338-P308+P313
[Safety Statements ]

24/25
[WGK Germany ]

3
[RTECS ]

YU7100000
[F ]

10-21
[TSCA ]

Yes
[HS Code ]

35079090
[Storage Class]

6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
[Hazard Classifications]

Eye Irrit. 2
Repr. 1B
Resp. Sens. 1
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