| Identification | Back Directory | [Name]
ACETATE KINASE | [CAS]
9027-42-3 | [Synonyms]
AK
WEL
EC 2.7.2.1
EC: 2.7.2.1
Acetokinase
Acetic kinase
ACETATE KINASE
AWELLS human cell line
ACETATE KINASE LYOPHILIZED
ATP: ACETATE PHOSPHOTRANSFERASE
Kinase (phosphorylating), acetate
ACETATE KINASE FROM ESCHERICHIA COLI
Native Escherichia coli Acetate Kinase
Kinase (phosphorylating), acetate (9CI)
Acetate Kinase Bacillus stearothermophilus
acetate kinase from methanosarcina thermophila
ACETATE KINASE FROM BACILLUSSTEAROTHERMO PHILUS
ACETATE KINASE FROM E. COLI, ~150 U/MG P ROTEIN
Auto-Activated Protein Kinase from bovine kidney
Native Bacillus stearothermophilus Acetate Kinase
ACETATE KINASE FROM METHANOSARCINATHERMO PHILA RECO | [EINECS(EC#)]
232-818-0 | [MDL Number]
MFCD00130330 |
| Chemical Properties | Back Directory | [storage temp. ]
2-8°C | [form ]
lyophilized powder | [color ]
Colorless to light yellow | [biological source]
human blood | [Specific Activity]
400-1,200units/mg solid |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
22 | [Safety Statements ]
24/25 | [RIDADR ]
UN 1789 8 / PGIII | [WGK Germany ]
3 | [F ]
10 | [Storage Class]
8A - Combustible corrosive hazardous materials | [Hazard Classifications]
Met. Corr. 1 |
| Hazard Information | Back Directory | [Uses]
Acetate kinase is used to phosphorylate acetate to acetyl phosphate. Acetate Kinase from Bacillus stearothermophilus has been used to study allosteric activation. [32P]-acetyl phosphate was generated by incubating potassium acetate in the reaction mixture with acetate kinase from Sigma. This [32P]-acetyl phosphate was used to label BldM, BldM D-54N or BldM D-54A loci during the study of the effect of bldM gene on Streptomyces coelicolor development. | [Uses]
Acetate kinase is used to phosphorylate acetate to acetyl phosphate. Acetate Kinase from Escherichia coli has been used as part of an ATP-regenerating system to study the kinetics of agonist-stimulated transphosphatidylation . | [General Description]
Acetate kinase belongs to acetate and sugar kinase/Hsc70/actin (ASKHA) structural superfamily. It exists as a dimer and has nucleotide binding site in the cleft between N and C-terminal domain. | [Biochem/physiol Actions]
Acetate kinase plays an important role in glycolysis. Acetate kinase phosphorylates acetate in the presence of ATP and a divalent cation, which ultimately results in the production of acetyl-CoA. Acetate kinase is also involved in the metabolism of propanoate, pyruvate and taurine. Acetate Kinase from Bacillus stearothermophilus is a thermostable tetramer of identical subunits with molecular weight of 40,000 Da each. The enzyme does not have a -SH group and is composed of 36% β-structure, 21 % α-helix and 43 % unordered structure. |
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| Company Name: |
Sigma-Aldrich
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| Telephone: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
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