| Identification | More | [Name]
Ropinirole | [CAS]
91374-21-9 | [Synonyms]
4-(2-dipropylaminoethyl)-1,3-dihydroindol-2-one
ROPINIROLE
ROPINIROLE 99%
ROPINIROLE: ROPINIROLE HYDROCHLORIDE
ROPINIROLE INTERMEIDATES:
4-[2-(Dipropylamino)ethyl]-1，3-dihydrcr2H-indol-2-one
SKF-101468
SKF-101468A：ReQuip
4-[2-(Dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-one
4-[2-(Dipropylamino)ethyl]indoline-2-one | [Molecular Formula]
C16H24N2O | [MDL Number]
MFCD00864147 | [Molecular Weight]
260.37 | [MOL File]
91374-21-9.mol |
| Hazard Information | Back Directory | [Uses]
Antiparkinsonian (D2receptor agonist). | [Definition]
ChEBI: Ropinirole is a member of indolones and a tertiary amine. It has a role as a dopamine agonist, an antiparkinson drug, a central nervous system drug and an antidyskinesia agent. | [Brand name]
Requip (GlaxoSmithKline). | [Synthesis Reference(s)]
Journal of Medicinal Chemistry, 28, p. 1533, 1985 DOI: 10.1021/jm00148a028 | [Clinical Use]
Anti-Parkinson agent
Restless legs syndrome (RLS) | [Drug interactions]
Potentially hazardous interactions with other drugs
Antipsychotics: antagonism of anti-Parkinsonian
effect - avoid.
Metoclopramide: antagonism of anti-Parkinsonian
effect - avoid.
Oestrogens: concentration increased. | [Metabolism]
Ropinirole is hepatically metabolised by the cytochrome
P450 enzyme, CYP1A2, and excreted in the urine as
inactive metabolites. |
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