| Identification | More | [Name]
2,3-Dihydroxynaphthalene | [CAS]
92-44-4 | [Synonyms]
2,3-DIHYDROXYNAPHTHALENE
2,3-NAPHTHALENEDIOL
2,3-Dihydroxynapthalene
Naphthalene-2,3-diol
Naphthalenediol-(2,3)
2,3-DIHYDROXYNAPHTHALENE, SUBL.
2 3-DIHYDROXYNAPHTHALENE 98%
2,3-DihydroxylNaphthalene
Dihydroxynaphthalene
2,3-Dihydroxynaphthalene,98%
2,3-Dihydroxy
2,3-Dihydroxynaphthylene
2,3-dihydrroxynaphthalene | [EINECS(EC#)]
202-156-7 | [Molecular Formula]
C10H8O2 | [MDL Number]
MFCD00004073 | [Molecular Weight]
160.17 | [MOL File]
92-44-4.mol |
| Chemical Properties | Back Directory | [Appearance]
Off white to redish white powder | [Melting point ]
161-165 °C (lit.)
162-164 °C | [Boiling point ]
246.06°C (rough estimate) | [bulk density]
500kg/m3 | [density ]
1.0924 (rough estimate) | [vapor pressure ]
0.8 hPa (149 °C) | [refractive index ]
1.5178 (estimate) | [Fp ]
175 °C
| [storage temp. ]
Store below +30°C. | [solubility ]
4g/l | [form ]
Powder | [pka]
9.10±0.40(Predicted) | [color ]
White to pinkish to beige-grayish | [PH]
6 (1g/l, H2O, 20℃) | [Water Solubility ]
slightly soluble | [BRN ]
742375 | [Henry's Law Constant]
2.0×105 mol/(m3Pa) at 25℃, Ebert et al. (2023) | [Cosmetics Ingredients Functions]
HAIR DYEING | [Cosmetic Ingredient Review (CIR)]
2,3-Dihydroxynaphthalene (92-44-4) | [InChI]
1S/C10H8O2/c11-9-5-7-3-1-2-4-8(7)6-10(9)12/h1-6,11-12H | [InChIKey]
JRNGUTKWMSBIBF-UHFFFAOYSA-N | [SMILES]
Oc1cc2ccccc2cc1O | [CAS DataBase Reference]
92-44-4(CAS DataBase Reference) | [NIST Chemistry Reference]
2,3-Naphthalenediol(92-44-4) | [EPA Substance Registry System]
92-44-4(EPA Substance) |
| Safety Data | Back Directory | [Symbol(GHS) ]
 
GHS05,GHS07 | [Signal word ]
Danger | [Hazard statements ]
H302-H318 | [Precautionary statements ]
P264-P270-P280-P301+P312-P305+P351+P338-P501 | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S37/39:Wear suitable gloves and eye/face protection . | [WGK Germany ]
3
| [RTECS ]
QJ4750000
| [F ]
10-23 | [Autoignition Temperature]
>330 °C | [TSCA ]
Yes | [REACH Registrations]
Active | [HS Code ]
29072900 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral
Eye Dam. 1 | [Toxicity]
LD50 orally in Rabbit: 970 mg/kg |
| Raw materials And Preparation Products | Back Directory | [Raw materials]
2H-naphtho[2,3-d][1,3]dioxole-->(1aS,1bR,2aS,6bR)-1a,1b,2a,6b-Tetrahydronaphtho[1,2-b:3,4-b']bisoxirene-->Naphthalene-2,3-diol diacetate | [Preparation Products]
2,3-diaminonaphthalene-->4 5-Dichlorocatechol 97-->3-Methoxy-2-naphthol 97-->p-Toluic acid-->2,3-Dichloronaphthalene-->3-Amino-2-naphthol-->6,13-dihydrodibenzo[b,i]phenazine |
| Hazard Information | Back Directory | [Chemical Properties]
Off white to redish white powder | [Uses]
2,3-Naphthalenediol is used in cosmetics asa component of oxidative hair dye. It is usedat a concentration of <0.1%. | [Definition]
ChEBI: Naphthalene-2,3-diol is a naphthalenediol. | [General Description]
2,3-Dihydroxynaphthalene is a polyhydroxy phenol. It is an aromatic dihydroxy compound having hydroxyl groups at ortho positions. Its reaction with molybdenum(VI) complexes has been reported. The asymmetric oxidative coupling polymerization of 2,3-dihydroxynaphthalene using the Cu(I)-bisoxazoline complex as catalyst has been reported to afford poly(2,3-dihydroxy-1,4-naphthylene), having a continuous 1,1′-bi-2-naphthol main chain structure. The nitrodisplacement reaction between nitrophthalodinitriles and 2,3-dihydroxynaphthalene has been investigated. | [Health Hazard]
2,3-Naphthalenediol shows low toxicity andmild irritant actions on the skin and eyes. Theoral LD50 value for rats of a 5% solutionin propylene glycol may be on the orderof 675 mg/kg (calculated by the method ofWeil). The intravenous LD50 value for miceis 56 mg/kg. At 1% concentration, it causedslight eye irritation in female albino rabbitsand exhibited erythemal response in guineapigs. At the 0.1% level (concentration in hairdye), it had no reaction on human skin. Thiscompound was nonmutagenic in Salmonellatyphimurium strain tests.
There is very little information in the literatureon the toxicity of 2,3-naphthalenediol.Assessment by the CIR expert panel on thesafety of this compound as used in cosmeticshas been inconclusive (Cosmetic, Toiletryand Fragrance Association 1987b). | [Synthesis]
2,3-Dihydroxynaphthalene is prepared by caustic fusion of 3-hydroxynaphthalene-2,6-disulfonic acid followed by treatment with dilute sulfuric acid under pressure, or by acid desulfonation of 2,3-dihydroxynaphthalene-6-sulfonic acid. |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
|
| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
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