| Identification | Back Directory | [Name]
1-(1,3-Benzodioxol-5-yl)-N-[5-[(S)-(2-chlorophenyl)[(3R)-3-hydroxy-1-pyrrolidinyl]methyl]-2-thiazolyl]-cyclopropanecarboxamide | [CAS]
926664-32-6 | [Synonyms]
1-(1,3-Benzodioxol-5-yl)-N-[5-[(S)-(2-chlorophenyl)[(3R)-3-hydroxy-1-pyrrolidinyl]methyl]-2-thiazolyl]-cyclopropanecarboxamide
1-(benzo[d][1,3]dioxol-5-yl)-N-(5-((S)-(2-chlorophenyl)((R)-3-hydroxypyrrolidin-1-yl)methyl)thiazol-2-yl)cyclopropanecarboxamide
Cyclopropanecarboxamide, 1-(1,3-benzodioxol-5-yl)-N-[5-[(S)-(2-chlorophenyl)[(3R)-3-hydroxy-1-pyrrolidinyl]methyl]-2-thiazolyl]- | [Molecular Formula]
C25H24ClN3O4S | [MDL Number]
MFCD16659052 | [MOL File]
926664-32-6.mol | [Molecular Weight]
497.99 |
| Hazard Information | Back Directory | [Uses]
VRT-534 targets connexin 26 (Cx26). Vrt-534 exhibits dose-responsive binding to recombinant WT Cx26 and mutant Cx26 K188N with EC50 value of 19 μM and 5 μM, respectively. Vrt-534 can be used in research related to hearing impairment[1]. | [IC 50]
Cx26: 19 μM (EC50) | [References]
[1] Wang D, et al. A Chemical Chaperone Restores Connexin 26 Mutant Activity. ACS Pharmacol Transl Sci. 2023 Jun 1;6(7):997-1005. DOI:10.1021/acsptsci.3c00056 |
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DebyeTec.com Inc.
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18-086626237 18086626237 |
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www.chemicalbook.com/showsupplierproductslist16955/0.htm |
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