| Identification | Back Directory | [Name]
azetidin-3-ylmethanol hydrochloride | [CAS]
928038-44-2 | [Synonyms]
)azetidine hydrochL
Azetidine-3-methanol HCl
(azetidine-3-yl)Methanol hcl
3-(HydroxyMethyl)azetidine 3
3-(HydroxyMethyl)azetidine HCl
3-Azetidinemethanol hydrochloride
azetidin-3-ylmethanol hydrochloride
3-AzetidineMethanol,hydrochloride (1:1)
3-(Hydroxymethyl)azetidine hydrochloride
Azetidin-3-yl-methanol hydrochloride 97% | [EINECS(EC#)]
815-099-3 | [Molecular Formula]
C4H10ClNO | [MDL Number]
MFCD09743446 | [MOL File]
928038-44-2.mol | [Molecular Weight]
123.58 |
| Chemical Properties | Back Directory | [storage temp. ]
Inert atmosphere,Store in freezer, under -20°C | [form ]
powder to crystal | [color ]
White to Almost white | [Sensitive ]
Hygroscopic | [InChI]
InChI=1S/C4H9NO.ClH/c6-3-4-1-5-2-4;/h4-6H,1-3H2;1H | [InChIKey]
AQUVQGSNKVDBBF-UHFFFAOYSA-N | [SMILES]
C1NCC1CO.Cl |
| Hazard Information | Back Directory | [Uses]
3-Azetidinemethanol Hydrochloride is used in the synthesis of human rhinovirus inhibitors. | [Synthesis]
General procedure for the synthesis of 3-methylhydroxyazetidine hydrochloride from 1-Boc-3-hydroxymethylazetidine: compound 1-Boc-3-hydroxymethylazetidine (0.100 g, 0.534 mmol) was dissolved in dichloromethane (2 mL), followed by the addition of a solution of hydrogen chloride in dioxane (1 mL, 4 M). The reaction mixture was stirred at room temperature for 20 hours. After completion of the reaction, the mixture was concentrated to afford the target product 3-methylhydroxyazetidine hydrochloride (white solid, 0.060 g, yield: 90.91%). | [References]
[1] Patent: CN105732602, 2016, A. Location in patent: Paragraph 0410; 0411; 0412; 0413; 0414; 0415
[2] Patent: US2018/16252, 2018, A1. Location in patent: Paragraph 1112 |
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J & K SCIENTIFIC LTD.
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18210857532 18210857532 |
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https://www.jkchemical.com |
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Alfa Aesar
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400-6106006 |
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http://chemicals.thermofisher.cn |
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Energy Chemical
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400-0056266 |
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www.energy-chemical.com |
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Jia Xing Isenchem Co.,Ltd
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0573-85285100 18627885956 |
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