ChemicalBook--->CAS DataBase List--->935545-74-7

935545-74-7

935545-74-7 Structure

935545-74-7 Structure
IdentificationBack Directory
[Name]

SPINETORAM STANDARD
[CAS]

935545-74-7
[Synonyms]

SPINETORAM STANDARD
Spinetoram in Methanol solution
[Molecular Formula]

C42H69NO10·C43H69NO10
Chemical PropertiesBack Directory
[storage temp. ]

-20°C
[solubility ]

DMF: 30 mg/ml; DMSO: 5 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS (pH 7.2) (1:3): 0.25 mg/ml
[form ]

A crystalline solid
[Major Application]

cannabis testing
[EPA Substance Registry System]

Spinetoram (935545-74-7)
Safety DataBack Directory
[Symbol(GHS) ]

Health Hazard (GHS08)Exclamation Mark (GHS07)Environment (GHS09)
GHS08,GHS07,GHS09
[Signal word ]

Warning
[Hazard statements ]

H410-H361f-H317-H400
[Precautionary statements ]

P273-P391-P501-P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P273-P391-P501
[WGK Germany ]

WGK 2
[Storage Class]

3 - Flammable liquids
[Hazard Classifications]

Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Eye Irrit. 2
Flam. Liq. 2
Hazard InformationBack Directory
[Description]

Spinetoram is an insecticide and a semisynthetic derivative of the insecticide spinosad . Spinetoram is a mixture of 3’-ethyl-5,6-dihydrospinosyn J and 3’-ethoxy-spinosyn L . It induces mortality in H. armigera third, fourth, and fifth instar larvae when administered in the diet at 0.19 and 0.36 mg/kg and decreases pupal survival and adult emergence in surviving larvae. It also induces mortality of wild-type D. melanogaster but not D. melanogaster containing a genetic mutation in the Dα6 subunit of the nicotinic acetylcholine receptor (nAChR; LC50s = 0.025 and 4.4 μg/cm2, respectively, administered in the diet). Formulations containing spinetoram have been used as insecticides in agriculture.
[Uses]

Spinetoram belongs to spinosyn family of insecticides and shows potential of natural products research.
[Definition]

ChEBI: Spinetoram is an organic molecular entity.
[References]

[1] KIRST H A. The spinosyn family of insecticides: realizing the potential of natural products research[J]. Journal of Antibiotics, 2010, 63 3: 101-111. DOI: 10.1038/ja.2010.5
[2] JIZHEN WEI. Assessment of the lethal and sublethal effects by spinetoram on cotton bollworm.[J]. PLoS ONE, 2018: e0204154. DOI: 10.1371/journal.pone.0204154
[3] GERALD B. WATSON . A spinosyn-sensitive Drosophila melanogaster nicotinic acetylcholine receptor identified through chemically induced target site resistance, resistance gene identification, and heterologous expression[J]. Insect Biochemistry and Molecular Biology, 2010, 40 5: Pages 376-384. DOI: 10.1016/j.ibmb.2009.11.004
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