| Identification | More | [Name]
Butyl 4-aminobenzoate | [CAS]
94-25-7 | [Synonyms]
4-AMINOBENZOIC ACID BUTYL ESTER
4-AMINOBENZOIC ACID N-BUTYL ESTER
BUTAMBEN
BUTOFORM
BUTYL 4-AMINOBENZOATE
BUTYL 4-AMINOBENZOIC ACID
BUTYL-P-AMINOBENZOATE
BUTYL-PARA-AMINOBENZOATE
LABOTEST-BB LT00053674
N-BUTYL 4-AMINOBENZOATE
N-BUTYL P-AMINOBENZOATE
P-AMINOBENZOIC ACID BUTYL ESTER
PLANOFORM
TIMTEC-BB SBB007542
4-(Butoxycarbonyl)aniline
4-amino-benzoicacibutylester
Benzoic acid, 4-amino-, butyl ester
Benzoic acid, p-amino-, butyl ester
Butesin
Butesine | [EINECS(EC#)]
202-317-1 | [Molecular Formula]
C11H15NO2 | [MDL Number]
MFCD00017112 | [Molecular Weight]
193.24 | [MOL File]
94-25-7.mol |
| Chemical Properties | Back Directory | [Melting point ]
57-58 °C(lit.) | [Boiling point ]
174 °C8 mm Hg(lit.) | [density ]
1.0945 (rough estimate) | [refractive index ]
1.5480 (estimate) | [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
pKa 5.38 (Uncertain) | [color ]
White | [Water Solubility ]
Very slightly soluble in water. | [Sensitive ]
Light Sensitive | [Merck ]
1512 | [BRN ]
1211465 | [Major Application]
pharmaceutical (small molecule) | [Cosmetics Ingredients Functions]
UV ABSORBER | [InChI]
1S/C11H15NO2/c1-2-3-8-14-11(13)9-4-6-10(12)7-5-9/h4-7H,2-3,8,12H2,1H3 | [InChIKey]
IUWVALYLNVXWKX-UHFFFAOYSA-N | [SMILES]
CCCCOC(=O)c1ccc(N)cc1 | [LogP]
2.870 | [CAS DataBase Reference]
94-25-7(CAS DataBase Reference) | [NIST Chemistry Reference]
Butamben(94-25-7) | [EPA Substance Registry System]
94-25-7(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin .
R43:May cause sensitization by skin contact. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37:Wear suitable protective clothing and gloves .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [RTECS ]
DG1530000
| [TSCA ]
Yes | [HS Code ]
29224999 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Eye Irrit. 2
Skin Irrit. 2
Skin Sens. 1
STOT SE 3 | [Hazardous Substances Data]
94-25-7(Hazardous Substances Data) |
| Hazard Information | Back Directory | [General Description]
Yellow powder. Insoluble in water. | [Reactivity Profile]
N-BUTYL-P-AMINOBENZOATE(94-25-7) is an aminophenyl ester derivative. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides. | [Air & Water Reactions]
May be sensitive to light and air. Insoluble in water. Slowly hydrolyzed when boiled in water. Also will hydrolyze under high and low pH conditions . | [Fire Hazard]
Flash point data for this chemical are not available. N-BUTYL-P-AMINOBENZOATE is probably combustible. | [Chemical Properties]
It is a solid at room temperature,
with a melting point of 58°C and a boiling point of
173.4°C (at 8mmHg). Butyl p-aminobenzoate is insoluble
in water. | [Uses]
antibacterial | [Uses]
n-Butyl 4-aminobenzoate is used as pharmaceutical intermediate. | [Definition]
ChEBI: An amino acid ester resulting from the formal condensation of the carboxy group of 4-aminobenzoic acid with the hydroxy group of butan-1-ol. Its local anaesthetic properties have been used for surface anaesthesia of the skin and mucous membranes, and for r
lief of pain and itching associated with some anorectal disorders. | [Production Methods]
Butyl p-aminobenzoate is manufactured via esterification of
p-nitrobenzoic acid with n-butyl alcohol, followed by the
reduction of the nitro group to an amino group. | [Brand name]
Butesin
(Abbott). | [Purification Methods]
Crystallise Butamben from EtOH. [Beilstein 14 IV 1130.] | [References]
[1] Tetrahedron Letters, 1996, vol. 37, # 35, p. 6375 - 6378
[2] Carbohydrate Research, 2012, vol. 361, p. 1 - 6
[3] Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 14, p. 1245
[4] Russian Journal of Organic Chemistry, 1995, vol. 31, # 11, p. 1529 - 1532
[5] Zhurnal Organicheskoi Khimii, 1995, vol. 31, # 11, p. 1701 - 1704 |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
|
| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
| Company Name: |
Maya High Purity Chemicals
|
| Telephone: |
+86 (573) 82222445 (0)18006601000 452520369 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList15221/0_EN.htm |
| Company Name: |
Spectrum Chemical Manufacturing Corp.
|
| Telephone: |
021-021-021-67601398-809-809-809 15221380277 |
| Website: |
www.spectrumchemical.com/oa_html/index.jsp?minisite=10020&respid=22372&language=us |
|