| Identification | Back Directory | [Name]
2,3-dichloro-N-(5-fluoro-3-methoxy-pyrazin-2-yl)benzenesulfonamide | [CAS]
942137-41-9 | [Synonyms]
AZD-1678)
AZD 1678
(AZD1678
2,3-dichloro-N-(6-fluoro-3-methoxypyrazin-2-yl)benzenesulfonamide
2,3-dichloro-N-(5-fluoro-3-methoxy-pyrazin-2-yl)benzenesulfonamide
Benzenesulfonamide, 2,3-dichloro-N-(5-fluoro-3-methoxy-2-pyrazinyl)- | [EINECS(EC#)]
814-231-7 | [Molecular Formula]
C11H8Cl2FN3O3S | [MDL Number]
MFCD28975034 | [MOL File]
942137-41-9.mol | [Molecular Weight]
352.17 |
| Chemical Properties | Back Directory | [Boiling point ]
469.8±55.0 °C(Predicted) | [density ]
1.622±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
5.54±0.40(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Uses]
AZD-1678 is a potent CCR4 receptor antagonist, with a pIC50 of 8.6[1]. | [References]
[1] Nicholas Kindon, et al. Discovery of AZD-2098 and AZD-1678, Two Potent and Bioavailable CCR4 Receptor Antagonists. ACS Med Chem Lett. 2017 Sep 1;8(9):981-986. DOI:10.1021/acsmedchemlett.7b00315 |
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