| Identification | Back Directory | [Name]
Senkyunolide H | [CAS]
94596-27-7 | [Synonyms]
Senkyunolide H
Dimethyl 3-oxo-3H-pyrrolo[2,1,5-de]quinolizine-1,2-dicarboxylate
(3Z,6R,7S)-rel-3-Butylidene-4,5,6,7-tetrahydro-6,7-dihydroxy-1(3H)-isobenzofuranone
1(3H)-Isobenzofuranone, 3-butylidene-4,5,6,7-tetrahydro-6,7-dihydroxy-, (3Z,6R,7S)-rel- | [Molecular Formula]
C12H16O4 | [MDL Number]
MFCD32182625 | [MOL File]
94596-27-7.mol | [Molecular Weight]
224.25 |
| Chemical Properties | Back Directory | [Boiling point ]
444.8±45.0 °C(Predicted) | [density ]
1.28 | [storage temp. ]
2-8°C | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Oil | [pka]
12.78±0.40(Predicted) | [color ]
White to off-white | [InChI]
InChI=1/C12H16O4/c1-2-3-4-9-7-5-6-8(13)11(14)10(7)12(15)16-9/h4,8,11,13-14H,2-3,5-6H2,1H3/b9-4-/t8-,11-/s3 | [InChIKey]
DQNGMIQSXNGHOA-SQTOKDDWNA-N | [SMILES]
C1(=O)C2=C(CC[C@@H](O)[C@H]2O)/C(=C/CCC)/O1 |&1:6,8,r| |
| Hazard Information | Back Directory | [Chemical Properties]
A slightly yellow oily substance, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from the rhizome of Chuanxiong. | [Uses]
Senkyunolide H is a phthalide isolated from the rhizome of Ligusticum chuanxiong Hort. Senkyunolide H has been reported to have several pharmacological activities, including anti-?atherosclerotic, antiproliferative, and cytoprotective effects. senkyunolide H protects against MPP+-induced apoptosis via the ROS-mediated mitogen-activated protein kinase pathway in PC12 cells. | [Definition]
ChEBI: Senkyunolide h is a member of 2-benzofurans. |
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