| Identification | Back Directory | [Name]
RHOIFOLIN | [CAS]
17306-46-6 | [Synonyms]
C12627
RHOIFOLIN
Rhoifoloside
RHOIFOLIN WITH HPLC
apigenin 7-O-hesperidoside
APIGENIN-7-RHAMNOGLUCOSIDE
APIGENIN-7-NEOHESPERIDOSIDE
Apigenin-7-O-rhamnoglucoside
APIGENIN 7-O-NEOHESPERIDOSIDE
APIGENIN-7-NEOHESPERIDOSIDE hplc
Rhoifolin, froM Turpinia Montana
Rhoifolin, 98%, from Turpinia montana
Apigenin 7-O-neohesperidoside
Rhoifolin
Rhoifolin, 98%, from Turpinia montana (Bl.) Kurz.
2-(4-Hydroxyphenyl)-5-hydroxy-7-(2-O-α-L-rhamnopyranosyl-β-D-glucopyranosyloxy)-4H-1-benzopyran-4-one
2-(4-Hydroxyphenyl)-5-hydroxy-7-[2-O-(α-L-rhamnopyranosyl)-β-D-glucopyranosyloxy]-4H-1-benzopyran-4-one
4H-1-Benzopyran-4-one,7-[[2-O-(6-deoxy-L-mannopyranosyl)-D-glucopyranosyl]oxy]-5-hydroxy-2-(4-hydroxyphenyl)-
7-[[2-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
7-[[2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl]oxy]-5-hydroxy-2-(4-hydroxyphenyl)-4H-benzopyran-4-one
7-((2-O-(6-Deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl)oxy)-5- hydroxy-2-(4-hydroxyphenyl)-4H-benzopyran-4-one
7-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-2-(4-hydroxyphenyl)chromen-4-one | [EINECS(EC#)]
241-335-4 | [Molecular Formula]
C27H30O14 | [MDL Number]
MFCD00016773 | [MOL File]
17306-46-6.mol | [Molecular Weight]
578.52 |
| Chemical Properties | Back Directory | [Melting point ]
250-265 °C(Solv: ethyl acetate (141-78-6)) | [Boiling point ]
916.5±65.0 °C(Predicted) | [density ]
1.69±0.1 g/cm3(Predicted) | [storage temp. ]
0-6°C | [solubility ]
Soluble in methan | [form ]
powder | [pka]
6.11±0.40(Predicted) | [color ]
Yellow | [biological source]
synthetic | [InChIKey]
RPMNUQRUHXIGHK-HNTVRLFJNA-N | [LogP]
-0.060 (est) |
| Hazard Information | Back Directory | [Chemical Properties]
Methanol is derived from the dried leaves of Turpinia arguya Seem of the Turpinaceae family. | [Uses]
antiinflammatory | [Uses]
Rhoifolin is a flavone, a type of flavonoid, a new natural glycoside of apigenin, has been obtained from the green leaves of Rhus succedanea. Rhoifolin has been shown to be an apigenin-7-rhamnoglucosi
de. Rhoifolin apparently is identical with the apigenin-7-rhamnoglucoside obtained by the bromination and dehydrobromination of Naringin (N378980). | [Definition]
ChEBI: Apigenin 7-O-neohesperidoside is an apigenin derivative having an alpha-(1->2)-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety attached to the 7-hydroxy group. It has a role as a metabolite. It is a neohesperidoside, a dihydroxyflavone and a glycosyloxyflavone. It is functionally related to an apigenin. | [in vivo]
Rhoifolin (12, 24, 30, 36, and 40 mg/kg; PO, for 7 days) has radioprotective effect against radiation-induced decrease of blood platelets and cardiac biochemical lesions in whole body irradiated mice[4]. | Animal Model: | Swiss albino mice (10 Gy irradiation induced certain haematological and cardiac biochemical abnormalities)[4] | | Dosage: | 12, 24, 30, 36, and 40 mg/kg | | Administration: | PO, for 7 days | | Result: | Diminished the toxic effect of radiation by decreasing the level of lipid peroxides measured as malondialdehyde, ameliorating the alterations in nitric oxide, lactate dehydrogenase, creatine kinase in plasma and tissue and the plasma lipid profile. |
| [IC 50]
insulin receptor-β; GLUT4; NF-κB; MAPK |
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