ChemicalBook--->CAS DataBase List--->952-23-8

952-23-8

952-23-8 Structure

952-23-8 Structure
IdentificationBack Directory
[Name]

3,6-DIAMINOACRIDINE HYDROCHLORIDE
[CAS]

952-23-8
[Synonyms]

EUFLAVIN
nci-c04137
PROFLAVINESALTS
TIMTEC-BB SBB003182
PROFLAVINHYDROCHLORIDE
3,6-DiaminoacridineHCl
LABOTEST-BB LT00772201
PROFLAVINE HYDROCHLORIDE
PROFLAVIN MONOHYDROCHLORIDE
PROFLAVINE MONOHYDROCHLORIDE
3,6-DIAMINOACRIDINE HYDROCHLORIDE
acridine-3,6-diaMine hydrochloride
3,6-diamino-acridinmonohydrochloride
3,6-DIAMINOACRIDINE MONOHYDROCHLORIDE
3,6-Acridinediamine, monohydrochloride
3,6-diaminoacridinehydrochloridehemihydrate
2,8-diaminoacridiniumchloridemonohydrochloride
[EINECS(EC#)]

213-459-9
[Molecular Formula]

C13H12ClN3
[MDL Number]

MFCD00066867
[MOL File]

952-23-8.mol
[Molecular Weight]

245.71
Chemical PropertiesBack Directory
[Melting point ]

270°C (dec.) (lit.)
[storage temp. ]

Inert atmosphere,Room Temperature
[solubility ]

H2O: 1 mg/mL, clear
[form ]

powder
[Appearance]

Light brown to brown Solid
[Water Solubility ]

H2O: 1mg/mL, clear
[ε(extinction coefficient)]

50000 at 260nm in methanol
[λmax]

456 nm
[Major Application]

diagnostic assay manufacturing
hematology
histology
[InChI]

InChI=1S/C13H11N3.ClH/c14-10-3-1-8-5-9-2-4-11(15)7-13(9)16-12(8)6-10;/h1-7H,14-15H2;1H
[InChIKey]

PBBGTVBGXBUVLT-UHFFFAOYSA-N
[SMILES]

NC1C=CC2=CC3=CC=C(N)C=C3N=C2C=1.Cl
[EPA Substance Registry System]

Proflavine hydrochloride (952-23-8)
Hazard InformationBack Directory
[Definition]

ChEBI: A hydrochloride resulting from the reaction of equimolar amounts of 3,6-diaminoacridine and hydrogen chloride.
[General Description]

Brown powder.
[Air & Water Reactions]

Slightly soluble in water.
[Reactivity Profile]

3,6-DIAMINOACRIDINE HYDROCHLORIDE is amphoteric. Reacts both as a weak acid and as a weak base.
[Uses]

Acridine-3,6-diamine hydrochloride, canbe used for studying cation transfer at the liquid–liquid interface.
[Purification Methods]

It is first purified by precipitation of the free base by adding aqueous NH3 solution to an aqueous solution of the hydrochloride or hydrogen sulfate (see below), drying the precipitate and subliming at 0.01mm Hg [Müller & Crothers Eur J Biochem, 54 267 1975]. [Beilstein 22 H 487.]
Safety DataBack Directory
[WGK Germany ]

3
[RTECS ]

AR9064000
[Storage Class]

11 - Combustible Solids
[Safety Profile]

Poison by subcutaneous route. Questionable carcinogen. Mutation data reported. When heated to decomposition it emits very toxic fumes of NOx and HCl. Used as a drug, as a Isinfectant, and as a topical antiseptic.
Spectrum DetailBack Directory
[Spectrum Detail]

3,6-DIAMINOACRIDINE HYDROCHLORIDE(952-23-8)1HNMR
3,6-DIAMINOACRIDINE HYDROCHLORIDE(952-23-8)13CNMR
3,6-DIAMINOACRIDINE HYDROCHLORIDE(952-23-8)IR1
3,6-DIAMINOACRIDINE HYDROCHLORIDE(952-23-8)IR2
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