| Identification | Back Directory | [Name]
3-(4-fluorophenylaMino)-3-oxopropanoic acid | [CAS]
95262-10-5 | [Synonyms]
Cabozantinib Impurity 68
3-(4-fluorophenylaMino)-3-oxopropanoic acid | [Molecular Formula]
C9H8FNO3 | [MDL Number]
MFCD00201972 | [MOL File]
95262-10-5.mol | [Molecular Weight]
197.16 |
| Chemical Properties | Back Directory | [Melting point ]
142 °C(Solv: ethanol (64-17-5)) | [Boiling point ]
450.6±30.0 °C(Predicted) | [density ]
1.430±0.06 g/cm3(Predicted) | [pka]
-0.37±0.32(Predicted) |
| Hazard Information | Back Directory | [Synthesis]
Step 1: Synthesis of ethyl 3-(4-fluorophenylamino)-3-oxopropionate. Organic solution of diethyl malonate was added to organic solution of 4-fluorophenylamine and heated to reflux until the reaction was complete. The reaction solution was cooled |
|
|