| Identification | Back Directory | [Name]
Salvianolic acid | [CAS]
96574-01-5 | [Synonyms]
SALVIANOLIC ACID
SALVIANOLIC ACID A
Danphenolic acid A
Salvianolic acid A, >=98%
Salvianolic acid A hydrate
Dan phenolic acid A hydrate
Salvianolic acid A 96574-01-5
SALVIANOLIC ACID A 98.0% BY HPLC
Salvianolic acid A, froM Salvia Miltiorrhiza
Salvianolic acid A, 98%, from Salvia miltiorrhiza Bunge
(R)-3-(3,4-Dihydroxyphenyl)-2-(((E)-3-(2-((E)-3,4-dihydroxystyryl)-3,4-dihydroxyphenyl)acryloy
(R)-3-(3,4-Dihydroxyphenyl)-2-(((E)-3-(2-((E)-3,4-dihydroxystyryl)-3,4-dihydroxyphenyl)acryloyl)o
(R)-3-(3,4-Dihydroxyphenyl)-2-(((E)-3-(2-((E)-3,4-dihydroxystyryl)-3,4-dihydroxyphenyl)acryloyl)oxy)propanoic acid
(2R)-3-(3,4-Dihydroxyphenyl)-2-[(E)-3-[2-[(E)-2-(3,4-dihydroxyphenyl)ethenyl]-3,4-dihydroxyphenyl]prop-2-enoyl]oxypropanoic acid
(αR)-α-[[(2E)-3-[2-[(1E)-2-(3,4-Dihydroxyphenyl)ethenyl]-3,4-dihydroxyphenyl]-1-oxo-2-propen-1-yl]oxy]-3,4-dihydroxybenzenepropanoic acid
Benzenepropanoic acid, α-[[(2E)-3-[2-[(1E)-2-(3,4-dihydroxyphenyl)ethenyl]-3,4-dihydroxyphenyl]-1-oxo-2-propen-1-yl]oxy]-3,4-dihydroxy-, (αR)- | [Molecular Formula]
C26H22O10 | [MDL Number]
MFCD08458447 | [MOL File]
96574-01-5.mol | [Molecular Weight]
494.45 |
| Chemical Properties | Back Directory | [Melting point ]
164-167°C | [Boiling point ]
858.7±65.0 °C(Predicted) | [density ]
1.580±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
H2O: ≥19mg/mL | [form ]
powder | [pka]
2.78±0.10(Predicted) | [color ]
yellow | [Water Solubility ]
H2O: ≥19mg/mL | [BRN ]
2660108 | [InChIKey]
YMGFTDKNIWPMGF-UCPJVGPRSA-N | [SMILES]
C1(=C(C=CC(O)=C1O)C=CC(=O)O[C@H](CC1C=CC(O)=C(O)C=1)C(O)=O)C=CC1C=CC(O)=C(O)C=1 |t:9,28,&1:13,r| |
| Hazard Information | Back Directory | [Description]
Salvianolic acid A is an antioxidant and free radical scavenging compound extracted from S. miltiorrhiza that has been investigated for its cardioprotective and chemopreventative properties.1,2 It has been reported to reduce leukocyte-endothelial adherence, as well as inhibit inflammation and matrix metalloproteinases, suppress apoptosis, and reduce lipid peroxidation in damaged cardiac tissue.1,3 | [Chemical Properties]
Yellow Solid | [Uses]
ISalvianolic acid A (Sal A) and salvianolic acid B (Sal B) were isolated and purified from the crude extract of Salvia miltiorrhiza. Antioxidant activities of Sal A and Sal B were also evaluated
the ABTS results showed that Sal A and Sal B exhibited high total antioxidant activities, their EC50 values were 1.35 0.00 and 1.43 0.01 .mu.g/mL. | [Definition]
ChEBI: Salvianolic acid A is a stilbenoid. | [General Description]
Salvianolic acid A is a phenolic acid, isolated from Danshen, a traditional Chinese medicine, commonly used for the treatment of bone loss, chronic renal failure, hepatocirrhosis, hepatitis, coronary heart disease and cerebrovascular disease. | [Biochem/physiol Actions]
Salvianolic acid A is cell protective antioxidant originally isolated from Salvia. It has been found to attenuate PDGF-induced ROS formation in hepatic stellate cells and protected against isoproterenol-induced myocardial damage in rats. | [References]
[1] JENNIFER HUI-CHUN HO Chuang Y H. Salvianolic acids: small compounds with multiple mechanisms for cardiovascular protection.[J]. Journal of Biomedical Science, 2011: 30. DOI: 10.1186/1423-0127-18-30
[2] GENG-TAO LIU. Protective action of seven natural phenolic compounds against peroxidative damage to biomembranes[J]. Biochemical pharmacology, 1992, 43 2: Pages 147-152. DOI: 10.1016/0006-2952(92)90271-j
[3] HUAYING FAN. Cardioprotective effects of salvianolic Acid a on myocardial ischemia-reperfusion injury in vivo and in vitro.[J]. Evidence-based Complementary and Alternative Medicine, 2012: 508938. DOI: 10.1155/2012/508938 |
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