| Identification | Back Directory | [Name]
4-methylsulfinylphenyloxooxazolidinylmethylacetamide | [CAS]
96800-41-8 | [Synonyms]
DuP-105
4-methylsulfinylphenyloxooxazolidinylmethylacetamide
(5S)-5-Acetylaminomethyl-3-(4-methylsulfinylphenyl)oxazolidin-2-one
N-[[(5S)-3-[4-(Methylsulfinyl)phenyl]-2-oxooxazolidin-5-yl]methyl]acetamide
(S)-N-<<3-<4(S)-(methylsulfinyl)phenyl>-2-oxo-5-oxazolidinyl>methyl>acetamide
Acetamide, N-[[(5S)-3-[4-(methylsulfinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]- | [Molecular Formula]
C13H16N2O4S | [MDL Number]
MFCD31382166 | [MOL File]
96800-41-8.mol | [Molecular Weight]
296.34 |
| Hazard Information | Back Directory | [Uses]
DuP 105 is an orally active oxazolidinone, a new class of synthetic antimicrobial agent with activity against gram-positive bacteria. | [in vivo]
DuP 105 administered by either the oral or the parenteral route is protective against staphylococcal and streptococcal infections in mice with the 50% effective doses of 9 to 23 mg/kg[1]. | [IC 50]
Oxazolidinone | [storage]
Store at -20°C | [References]
[1] Slee AM, et al. Oxazolidinones, a new class of synthetic antibacterial agents: in vitro and in vivo activities of DuP 105 and DuP 721. Antimicrob Agents Chemother. 1987 Nov;31(11):1791-7. DOI:10.1128/AAC.31.11.1791
[2] Barry AL, et al. In vitro evaluation of DuP 105 and DuP 721, two new oxazolidinone antimicrobial agents. Antimicrob Agents Chemother. 1988 Jan;32(1):150-2. DOI:10.1128/AAC.32.1.150 |
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