126-27-2
中文名称
奥昔卡因
英文名称
Oxethazaine
CAS
126-27-2
EINECS 编号
204-780-5
分子式
C28H41N3O3
MDL 编号
MFCD00079202
分子量
467.64
MOL 文件
126-27-2.mol
126-27-2 结构式
基本信息
中文别名
2-双(N-甲基-N-苯基叔丁基-氨基甲酰甲基)氨基乙醇奥昔卡因
阿塞赛因
奥西卡因
羟乙卡因
英文别名
2-di(n-methyl-n-phenyl-tert-butyl-carbamoylmethyl)aminoethanol2-HYDROXYETHYLIMINOBIS-[N-(ALPHA,ALPHA-DIMETHYLPHENETHYL)-N-METHYLACETAMIDE]
OXETACAINE
OXETHAZAINE
OXETHAZINE
2,2’-((2-hydroxyethyl)imino)bis(n-(1,1-dimethyl-2-phenylethyl)-n-methylaceta
2,2’-((2-hydroxyethyl)imino)bis(n-(alpha,alpha-dimethylphenethyl)-n-acetamid
2,2’-((2-hydroxyethyl)imino)bis(n-(alpha,alpha-dimethylphenethyl)-n-methylac
acetamide,2,2’-(2-hydroxyethyl)imino)bis(n-(1,1-dimethylphenylethyl)-n-methy
betalgil
fh099
mucaine
mucoxin
mutesa
muthesa
n,n-bis(n-methyl-n-phenyl-tert-butylacetamido)-beta-hydroxyethylamine
oxaine
oxethacaina
oxethacaine
stomacain
所属类别
分析化学：法医和兽医标准品物理化学性质
熔点104-105°C
沸点570.1°C (rough estimate)
密度1.0974 (rough estimate)
折射率1.7800 (estimate)
储存条件Refrigerator
溶解度几乎不溶于水；易溶于甲醇；溶于乙酸乙酯。
酸度系数(pKa)14.62±0.10(Predicted)
形态neat
颜色白色至灰白色
水溶解性<0.1 g/100 mL at 23 ºC
EPA化学物质信息Oxethazaine (126-27-2)
常见问题列表
生物活性
Oxethazaine (Oxetacaine) 是芬特明的酸性前体，是一种具有耐酸性和口服活性的镇痛试剂。Oxethazaine (Oxetacaine) 具有缓解消化性溃疡疾病或食管炎引起的疼痛的潜力。体内研究
Oxetacaine (intraperitoneal injection; 5, 10, and 15 mg/kg; during days 4–11) doses induces significant conditioned place preference (CPP), and there are no differences among the groups. While its postive control group phentermine only 3 mg/kg causes significant CPP..
| Animal Model: | Male Wistar rats |
| Dosage: | 5, 10, and 15 mg/kg; during days 4–11 |
| Administration: | Intraperitoneal injection |
| Result: | Showed a significant CPP in vivo. |