127-31-1
中文名称
氟氢可的松
英文名称
Fludrocortisone
CAS
127-31-1
EINECS 编号
204-833-2
分子式
C21H27FO5
MDL 编号
MFCD00083333
分子量
378.43
MOL 文件
127-31-1.mol
更新日期
2024/04/23 17:26:38
127-31-1 结构式
基本信息
中文别名
氟氢可的松 英文别名
4-PREGNEN-9-ALPHA-FLUORO-11-BETA, 17,21-TRIOL-3,20-DIONE4-PREGNEN-9ALPHA-FLUORO-11BETA, 17ALPHA, 21-TRIOL-3, 20-DIONE
4-PREGNENE-9-ALPHA-FLUORO-11-BETA,17-ALPHA,21-TRIOL-3,20-DIONE
9a-fluoro-11b,17a,21-trihydroxy-4-pregnene-3,20-dione
9a-fluoro-17-hydroxycorticosterone
9-ALPHA-FLUORO-11-BETA,17-ALPHA,21-TRIHYDROXY-4-PREGNENE-3,20-DIONE
9-ALPHA-FLUOROHYDROCORTISONE
9-FLUOROCORTISOL
FLUDROCORTISONE
FLUOROCORTISONE
17,21-trihydroxy-20-dion(11beta)-pregn-4-ene-9-fluoro-11
9alpha-fludrocortisone
9-alpha-fluoro-17-hydroxycorticosterone
9alpha-fluoro-17-hydroxycorticosterone
9-alpha-fluorocortisol
9alpha-fluorocortisol
9-fluoro-11-beta,17,21-trihydroxy-pregn-4-ene-20-dione
9-fluoro-11beta,17,21-trihydroxy-pregn-4-ene-20-dione
9-fluoro-11-beta,17,21-trihydroxypregn-4-ene-3,20-dione
9-fluorohydrocortisone
所属类别
原料药：肾上腺皮质激素类药物理化学性质
熔点208-212°C
比旋光度D23 +139° (c = 0.55 in 95% ethanol)
沸点564.7±50.0 °C(Predicted)
密度1.1176 (estimate)
储存条件Refrigerator
溶解度可溶于DMSO（轻微）、乙醇（轻微、加热）、甲醇（轻微、超声处理）
酸度系数(pKa)12.11±0.70(Predicted)
形态固体
颜色白色至灰白色
水溶解性111mg/L(25 ºC)
