146-14-5
146-14-5 结构式
基本信息
氟-氨碇
腺嘌呤黄素
黄素腺嘌呤二核苷酸
核黄素腺苷双核苷酸
二核苷酸黄素腺嘌呤
二核苷酸核黄素腺苷
腺嘌呤黄素二核苷酸
腺[嘌呤]黃素二苷酸
Β-黄素腺嘌呤二核苷酸
flavinat
flavitan
Flavinin
Wakadenin
NSC 112207
Flavine Adenine
5'-ester with adenosine
flavinadenindinucleotide
adenine-flavindinucleotide
物理化学性质
常见问题列表
黄素腺嘌呤二核苷酸（英语：FAD），又称活性型维生素B2、核黄素-5'-腺苷二磷酸，是一种参与了重要的代谢反应的氧化还原辅酶。FAD是一种比NAD和NADP更强的氧化剂，能被1个电子或2个电子途径还原。其可用于标记黄嘌呤腺嘌呤氧化酶，核黄素激酶肿瘤坏死因子受体1 NADPH氧化酶。
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Human Endogenous Metabolite
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Poly(Flavin adenine dinucleotide, FAD) characterized by an additional polymer-type redox reaction is a highly effective electrocatalyst for NADH oxidation: operating at the lowest potentials reported for NADH transducers (0.00 V, pH 7.4), poly(FAD) is characterized by the electrochemical rate constant of 1.8 ± 0.6×10 -3 cm/s, which is at the level of the NADH mass-transfer constant. Poly(FAD)-modified electrodes are characterized by the dramatically improved stability and, is the most advantageous NADH transducers for analytical chemistry.
Flavin adenine dinucleotide (2 mg/kg, i.v.) significantly cancels chlorpromazine (CPZ)-induced decrease in ventricular fibrillation threshold (VFT). Flavin adenine dinucleotide cancels the effect of CPZ on canine heart mitochondria. After injection of Flavin adenine dinucleotide, the dogs show a transient hypotension within 10 min, then their blood pressures recover to the initial level. Flavin adenine dinucleotide also prevents mitochondrial dysfunction induced by chlorpromazine.