196961-43-0
中文名称
3-[4-Hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-2-propenoicacid
英文名称
3-[4-Hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-2-propenoicacid
CAS
196961-43-0
分子式
C24H28O3
分子量
364.48
MOL 文件
196961-43-0.mol
196961-43-0 结构式
基本信息
中文别名
化合物 T14912 英文别名
CD 32543-[4-Hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-2-propenoicacid
2-Propenoic acid, 3-[4-hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-
物理化学性质
熔点165 - 167°C
沸点508.0±50.0 °C(Predicted)
密度1.108±0.06 g/cm3(Predicted)
储存条件-20°C储存
溶解度可溶于DMSO（少许）、甲醇（少许）
酸度系数(pKa)4.61±0.10(Predicted)
形态固体
颜色白色至灰白色
常见问题列表
生物活性
CD3254 是一种有效的选择性类视黄醇 X 受体 (RXR) 激动剂。靶点
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RXR
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体外研究
CD3254 induces similar phenotypes of malformations after 5 days exposure at low concentration (20 μg/L) to those after the 1st d exposure at high concentrations (50 and 100 μg/L).
Cell Viability Assay
| Cell Line: | zebrafish ( Danio rerio ) embryos |
| Concentration: | 10, 20, 50, 100 μg/L |
| Incubation Time: | |
| Result: | The percent of survival decreased by 19.1 % in 100 μg/L CD3254-treated group after the 1st day exposure. The embryos did not hatch in groups exposed to 100 μg/L CD3254 for 5 days or to 1 mg/L CD3254 for the 1st day. |