2491-18-1
2491-18-1 结构式
基本信息
L-蛋氨酸甲脂盐酸盐
蛋氨酸甲酯盐酸盐
L-蛋氨酸甲酯盐酸盐
L-甲硫氨酸甲酯盐酸盐
L-环丙氨酸甲酯
L-甲硫氨酸甲酯盐酸盐/L-蛋氨酸甲酯盐酸盐
H-MET-OME HYDROCHLORIDE
L-METHIONINE METHYL ESTER HYDROCHLORIDE
L-METHIONINE METHYL ESTER HYDROCHLORIDE SALT
METHIONINE-OME HCL
methyl L-methionate hydrochloride
L-Methionine Methyl Ester HCl
H-MET-OME.HCLL-METHIONINE METHYL ESTER HYDROCHLORIDE
H-Met-OMeCl
L-Methioninemethylesterhydrochloride,99%
H-Met-OMe•
H-L-Met-OMe*HCl
(2S)-2-Amino-4-methylsulfanylbutanoate hydrochloride
物理化学性质
制备方法
67-56-1
63-68-3
2491-18-1
合成实施例1：将L-蛋氨酸（0.5 g，1当量）悬浮于装有磁力搅拌子的100 mL圆底烧瓶中，加入甲醇（30 mL，浓度为0.1 M），并在氮气氛围下冷却至0℃。缓慢滴加亚硫酰氯（0.5 mL，2当量）至上述悬浮液中，随后加热回流反应16小时。反应完成后，通过旋转蒸发仪除去溶剂，得到浅黄色固体。将该固体用热乙醚研磨，过滤去除乙醚溶液，得到白色固体L-蛋氨酸甲酯盐酸盐（0.65561 g，收率98%）。产物经真空干燥进一步纯化。1H NMR (D2O, 500 MHz) δH: 4.24 (1H, m, CH), 3.79 (3H, s, OCH3), 2.63 (2H, t, CH2), 2.25 (1H, m, CH2), 2.16 (1H, m, CH2), 2.06 (1H, s, SCH3). 13C NMR (D2O, 125 MHz) δC: 170.58 (C=O), 53.64 (OCH3), 51.70 (CH), 28.71 (CH2), 28.41 (CH2), 13.85 (SCH3). IR (neat, vmax, cm-1): 2880.8/2676.2 (CH3, CH2, CH), 2016.2, 1742.2 (C=O, ester), 1483.6, 1443.5, 1227, 1194.7, 1149.8, 1079.5 (C-O). HRMS m/z (+ESI): C6H14NO2S, calculated mass = 164.074 (error = 0.07 ppm).
参考文献：
[1] Journal of Organic Chemistry, 2011, vol. 76, # 1, p. 201 - 215
[2] Journal of the American Chemical Society, 2017, vol. 139, # 40, p. 14077 - 14089
[3] Patent: WO2012/131313, 2012, A1. Location in patent: Page/Page column 49
[4] Patent: US2014/39200, 2014, A1. Location in patent: Paragraph 0376-0380
[5] Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2006, vol. 45, # 8, p. 1942 - 1944
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2025/09/19 | A15952 | L-蛋氨酸甲酯盐酸盐, 99% L-Methionine methyl ester hydrochloride, 99% | 2491-18-1 | 25g | 594元 |
| 2025/09/19 | 22935 | L-蛋氨酸甲酯盐酸盐 L-Methionine methyl ester hydrochloride, 98% | 2491-18-1 | 25g | 2818元 |
| 2025/05/22 | A15952 | L-蛋氨酸甲酯盐酸盐, 99% L-Methionine methyl ester hydrochloride, 99% | 2491-18-1 | 5g | 306元 |