3376-24-7
3376-24-7 结构式
基本信息
N-叔丁基-#-苯基硝酮
N-叔丁基-а-苯基硝酮
N-苯亚甲基叔丁胺-N-氧化物
N-叔丁基-Α-苯基硝酮
N-叔丁基-A-苯硝酮
N-叔丁基-Α-苯基硝酸灵
N-BENZYLIDENE-TERT-BUTYLAMINE N-OXIDE
N-T-BUTYL-ALPHA-PHENYLNITRONE
N-TERT-BUTYL-ALPHA-PHENYLNITRONE
N-TERT-BUTYL-A-PHENYLNITRONE
PBN
PHENYL N-TERT-BUTYLNITRONE
2-methyl-n-(phenylmethylene)-2-propanaminn-oxide
2-methyl-n-(phenylmethylene)-s-propanaminen-oxide
2-methyl-n-(phenylmethylene)-s-propanaminn-oxide
2-phenyl-n-tert-butylnitrone
alpha-phenyl-n-tert-butylnitrone
Benzylidene(tert-butyl)azane oxide
benzylidene-tert-butylaminen-oxide
c-phenyl-n-tert-butylnitrone
n-benzylidene-tert-butylamineoxide
n-tert-butyl-2-phenylnitrone
n-tert-butyl-alpha-phenyl-nitron
n-tert-butyl-c-phenylnitrone
N-tert-Butyl-α-phenylnitrone
物理化学性质
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2024/01/25 | HY-128463 | N-叔丁基-#-苯基硝酮 N-tert-Butyl-α-phenylnitrone | 3376-24-7 | 100mg | 900元 |
| 2024/01/25 | HY-128463 | N-叔丁基-#-苯基硝酮 N-tert-Butyl-α-phenylnitrone | 3376-24-7 | 10mM * 1mLin DMSO | 990元 |
| 2024/01/25 | HY-128463 | N-叔丁基-#-苯基硝酮 N-tert-Butyl-α-phenylnitrone | 3376-24-7 | 250 mg | 1650元 |
常见问题列表
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COX-2
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Reactive oxygen species (ROS)
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N-tert-Butyl-α-phenylnitrone (PBN) (25-100 µM) treatment leads to a significant decrease in 2,2'-azobis (2-amidinopropane) dihydrochloride (AAPH)-induced intracellular ROS accumulation. N-tert-Butyl-α-phenylnitrone also attenuates AAPH-induced cytotoxicity, matrix degradation, and apoptosis. N-tert-Butyl-α-phenylnitrone suppresses AAPH-induced activation of ERK/MAPK pathway. N-tert-Butyl-α-phenylnitrone has the potenial for intervertebral disc degeneration (IDD) research.
N-tert-Butyl-α-phenylnitrone (PBN; 100 mg/kg; intraperitoneal injection; twice a day; C57Bl/6 mice) treatment not only abolishes the LPS-induced lipid peroxidation, nitrotyrosine residue levels, and GSH depletion, but also decreases the incidence of external malformations.
| Animal Model: | C57Bl/6 mice induced by lipopolysaccharide (LPS) |
| Dosage: | 100 mg/kg |
| Administration: | Intraperitoneal injection; twice a day (on gestational day 8) |
| Result: | Abolished LPS-induced lipid peroxidation, nitrotyrosine residues, and GSH depletion. |