化合物 T11556
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- CAS号:
- 339068-25-6
- 英文名:
- HET0016
- 英文别名:
- HET0016;HET0016,HET-0016;N-Hydroxy-N(4-butyl-2-methylphenyl)formamidine;N-HYDROXY-N'-(4-N-BUTYL-2-METHYLPHENYL)FORMANIDINE;N’-(4-Butyl-2-methylphenyl)-N-hydroxyformimidamide;N-(4-butyl-2-methylphenyl)-N'-hydroxyiminoformamide;N-(4-BUTYL-2-METHYLPHENYL)-N'-HYDROXY-METHANIMIDAMIDE;Methanimidamide, N'-(4-butyl-2-methylphenyl)-N-hydroxy-
- 中文名:
- 化合物 T11556
- 中文别名:
- 化合物 T11556;N'-(4-丁基-2-甲基苯基)-N-羟基甲脒;N-羟基-N'-(4-正丁基-2-甲基苯基)甲IDINE;N-(4-丁基-2-甲基苯基)-N'-羟基甲基亚氨基酰胺
- CBNumber:
- CB0149064
- 分子式:
- C12H18N2O
- 分子量:
- 206.28
- MOL File:
- 339068-25-6.mol
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化合物 T11556化学性质
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熔点:
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138-140°C
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储存条件:
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Hygroscopic, -20°C Freezer, Under inert atmosphere
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溶解度:
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Chloroform (Slightly), Ethanol (Slightly)
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形态:
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Light pink solid.
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颜色:
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White to Pale Yellow
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CAS 数据库:
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339068-25-6
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化合物 T11556性质、用途与生产工艺
用途
生物试剂
用途
HET-0016 is a potent and selective inhibitor of the biosynthesis of 20-HETE acting via inhibition of CYP4A (IC50=8.9nM (human), 35nM (rat renal microsome). IC50 cyclooxygenase=2.3uM. IC50 for other
CYP鈥檚: CYP2C9-3.3uM, CYP2D6=83.9 uM, CYP3A4=71uM. It inhibits cerebrovascular constriction induced by Ca2+ or archidonate and inhibits angiogenesis and endothelial cell sprouting in various models.
Displays protective effect on brain damage after temporary focal ischemia (at 10mg/Kg).
化合物 T11556
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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| 2024/04/30 | HY-124527 | HET0016 | | 1 mg | 250元 |
| 2024/04/30 | HY-124527 | HET0016 | 339068-25-6 | 10mM * 1mLin DMSO | 605元 |
339068-25-6, 化合物 T11556 相关搜索:
- Aromatics
- 小分子
- 羟化酶抑制剂
- 化合物 T11556
- N-羟基-N'-(4-正丁基-2-甲基苯基)甲IDINE
- N-(4-丁基-2-甲基苯基)-N'-羟基甲基亚氨基酰胺
- N'-(4-丁基-2-甲基苯基)-N-羟基甲脒
- 339068-25-6
- HET0016,HET-0016
- Methanimidamide, N'-(4-butyl-2-methylphenyl)-N-hydroxy-
- N’-(4-Butyl-2-methylphenyl)-N-hydroxyformimidamide
- N-(4-butyl-2-methylphenyl)-N'-hydroxyiminoformamide
- N-Hydroxy-N(4-butyl-2-methylphenyl)formamidine
- N-(4-BUTYL-2-METHYLPHENYL)-N'-HYDROXY-METHANIMIDAMIDE
- N-HYDROXY-N'-(4-N-BUTYL-2-METHYLPHENYL)FORMANIDINE
- HET0016